The healing effects of tissue glues and healing agent locally applied on esophageal anastomoses

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dc.contributor.authorYurtcu, Mueslim
dc.contributor.authorArbag, Hamdi
dc.contributor.authorToy, Hatice
dc.contributor.authorEryimaz, Mehmet Akif
dc.contributor.authorCaglayan, Osman
dc.contributor.authorAbasiyanik, Adnan
dc.date.accessioned2020-06-25T17:51:24Z
dc.date.available2020-06-25T17:51:24Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description27th Annual Meeting of the Turkish-Association-of-Pediatric-Surgeons -- OCT 02, 2009 -- Malatya, TURKEY
dc.description.abstractObjective: This study aimed to investigate the effects of cyanoacrylate (C), fibrin glue (FG), and natrium hyaluronate (NH) on the healing of esophageal anastomosis (EA). Methods: Twenty-four rabbits were divided equally into 4 groups: primary anastomosis (PA), C, FG, and NH. A 1-cm-length of the cervical esophagus was resected through a cervical incision and then anastomosis was performed. C, FG, and NH were instilled into anastomosis lines in the respective groups. The animals were fed orally on postoperative day 7 on the condition that there was no esophageal leakage. The rabbits were sacrificed 8 weeks later to evaluate bursting pressure (BP), tissue hydroxyproline (HP) levels and wound healing scores (WHSs) in the anastomosis lines. Results: BP was significantly higher in the C group than in the PA, FG, and NH groups, and HP was significantly lower than in the other groups. WHSs in the PA and NH groups were lower than in the C and FG groups. Conclusions: C and NH appear to be beneficial in EA healing with respect to increased BP and decreased HP when they are used simultaneously with PA prophylactically to prevent esophageal leakages and stricture. (C) 2009 Elsevier Ireland Ltd. All rights reserved.en_US
dc.description.sponsorshipTurkish Assoc Pediat Surgen_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.ijporl.2009.10.006
dc.identifier.endpage46en_US
dc.identifier.issn0165-5876
dc.identifier.issn1872-8464
dc.identifier.issue1en_US
dc.identifier.pmid19896727
dc.identifier.scopus2-s2.0-72649083151
dc.identifier.scopusqualityQ2
dc.identifier.startpage43en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2009.10.006
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4843
dc.identifier.volume74en_US
dc.identifier.wosWOS:000273901800008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal Of Pediatric Otorhinolaryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEsophageal anastomosisen_US
dc.subjectCyanoacrylateen_US
dc.subjectFibrin glueen_US
dc.subjectNatrium hyaluronateen_US
dc.titleThe healing effects of tissue glues and healing agent locally applied on esophageal anastomosesen_US
dc.typeArticle

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