The diagnostic value of pulmonary near-infrared spectroscopy in the early distinction of neonatal pneumonia from transient tachypnea of the newborn
[ X ]
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: Pulmonary near-infrared spectroscopy (NIRS) is a new and promising tool for diagnosis of neonatal respiratory diseases (RD). The study aimed to determine the role of pulmonary regional oxygen saturation (pRSO(2)) values obtained by NIRS in the early distinction of neonatal pneumonia (NP) from transient tachypnea of the newborn (TTN). Methods: This prospective, observational, double-blind study was conducted in neonatal intensive care unit (NICU) between 2020 and 2021. Late preterm and term newborns hospitalized in the NICU due to the diagnosis of TTN and NP were included. Cerebral RSO2 and pRSO(2) values were measured during the 1st, 24th, 48th, and 72nd hours of hospitalization, using NIRS. Results: Of the eligible 40 infants, 65% (n: 26) were diagnosed as TTN and 35% (n: 16) as NP. The pRSO(2) values were significantly higher in theTTN group than the NP group for both apexes (75.3 +/- 8.7 vs. 69 +/- 5.4, p:.018, respectively) and lateral lung (77.8 +/- 6 vs. 72.7 +/- 6.2, p:.016, respectively) in the 1st hour of hospitalization. There were significant differences in pRSO(2)apex and pRSO(2)lateral values between the 1st and 24th hours of hospitalization and the 24th and 48th hours in the NP group (p(2):.001 for both). The optimal pRSO(2)apex cut-off value was >72% to predict the diagnosis of NP with a sensitivity of 78.6% and a specificity of 69.2%. Conclusion: Pulmonary NIRS may be considered as a feasible and promising diagnostic tool in late preterm and term infants with RD. It may also be helpful for the early differentiation of NP from TTN and the courses of these diseases.
Açıklama
Anahtar Kelimeler
near-infrared spectroscopy; neonatal pneumonia; regional tissue oxygen saturation; respiratory distress; transient tachypnea of newborn
Kaynak
Pediatric Pulmonology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
58
Sayı
11
