Decreased choroidal thickness in vitiligo patients

dc.contributor.authorDemirkan, Serkan
dc.contributor.authorOnaran, Zafer
dc.contributor.authorSamav, Guzin
dc.contributor.authorOzkal, Fatma
dc.contributor.authorYumusak, Erhan
dc.contributor.authorGunduz, Ozgur
dc.contributor.authorKarabulut, Ayse
dc.date.accessioned2020-06-25T18:29:37Z
dc.date.available2020-06-25T18:29:37Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionGunduz, Ozgur/0000-0003-1021-5219;
dc.description.abstractBackground: Vitiligo is a disease characterized by depigmented macules and patches that occur as a result of the loss of functional melanocytes from the affected skin through a mechanism which has not been elucidated yet. Destruction of pigment cells in vitiligo may not remain limited to the skin; the eyelashes, iris, ciliary body, choroid, retinal pigment epithelium and meninges may also be affected. This study aims to compare the choroidal thickness of patients with and without vitiligo using optical coherence tomography (OCT). Methods: Spectral-domain optical coherence tomography (SD-OCT) (Retina Scan Advanced RS-3000 NIDEK, Japan) instrument (with lambda = 840 nm, 27,000 A-scans/second and 5 mu m axial resolution) was used for the imaging. Statistical analysis was performed using SPSS 21.0 software package. Results: In all values except optic nevre area measurements, the choroidal thickness of all vitiligo patients was found out to be thinner compared to the control group. Conclusions: In vitiligo, the choroidal thickness may be affected by the loss of melanocytes.en_US
dc.identifier.citationDemirkan, S., Onaran, Z., Samav, G. et al. (2018). Decreased choroidal thickness in vitiligo patients. BMC Ophthalmol 18, 126.en_US
dc.identifier.doi10.1186/s12886-018-0796-0
dc.identifier.issn1471-2415
dc.identifier.pmid29843674
dc.identifier.scopus2-s2.0-85047759309
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1186/s12886-018-0796-0
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7398
dc.identifier.volume18en_US
dc.identifier.wosWOS:000433949500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmcen_US
dc.relation.ispartofBmc Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVitiligoen_US
dc.subjectChoroidal thicknessen_US
dc.subjectOCTen_US
dc.subjectVASIen_US
dc.subjectOculocutaneous diseaseen_US
dc.titleDecreased choroidal thickness in vitiligo patientsen_US
dc.typeArticle

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