Esophageal and Gastric Smooth Muscle Activity After Carbon Dioxide Pneumoperitoneum

Basit Öğe Kaydı
dc.contributor.authorSoyer, Tutku
dc.contributor.authorAktuna, Zuhal
dc.contributor.authorAydos, Tolga Reşat
dc.contributor.authorOsmanoğlu, Gökhan
dc.contributor.authorKorkut, Oğuzhan
dc.contributor.authorAkman, Hülya
dc.contributor.authorÇakmak, Murat
dc.date.accessioned2020-06-25T17:49:28Z
dc.date.available2020-06-25T17:49:28Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description9th Annual Meeting of the British-Association-of-Paediatric-Endoscopic-Surgeons -- OCT 08-10, 2007 -- Istanbul, TURKEY
dc.descriptionAydos, Tolga Resat/0000-0002-1832-9336; Soyer, Tutku/0000-0003-1505-6042
dc.description.abstractBackground. The metabolic changes associated with carbon dioxide (CO(2)) pneumoperitoneum include metabolic acidosis and lowered intra-abdominal pH values. An experimental study was performed to evaluate the effect of CO(2) pneumoperitoneum on esophageal and gastric smooth muscle sensitivity in response to several agonists. Methods. Wistar albino rats, weighing 200-250 g, were allocated into three groups. After anesthetization with ketamine hydrochloride and xylazine, abdominal esophagus, gastroesophageal junction, and gastric fundus were removed via median laparotomy in the control group. In the oxygen (O(2)) group, a 16G catheter was inserted into the abdomen above the umbilicus and insufflated with 95% O(2) and 5% CO(2) with a pressure of 10 mm Hg. In the CO(2) group, CO(2) was insufflated at the same pressure within the same time and the tissues were removed at the end of a 60 min period of pneumoperitoneum. Abdominal esophageal segment (n:6), gastroesophageal junction (n:6) and gastric fundus (n:12) were suspended under 0.5 to 2 g resting tension in Tyrode solution in organ baths. Contraction responses were obtained by carbachol and serotonin and relaxation responses were evaluated by isoproterenol in each group. All the responses were compared by nonparametric Kruskal Wallis test. Results. Carbachol and serotonin induced contractile responses of abdominal segments, gastroesophageal junction, and gastric fundus showed no difference between the control, O(2), and CO(2) groups (P > 0.05). Isoproterenol relaxation responses of the three groups were also not statistically different from each other (P > 0.05). Conclusion. CO(2) pneumoperitoneum of 60 min has no influence on esophageal and gastric smooth muscle responses to different agonists in rats. (C) 2010 Elsevier Inc. All rights reserved.en_US
dc.description.sponsorshipBritish Assoc Paediat Endoscop Surgen_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.jss.2009.02.009
dc.identifier.endpage281en_US
dc.identifier.issn0022-4804
dc.identifier.issue2en_US
dc.identifier.pmid19524263
dc.identifier.scopus2-s2.0-77951937955
dc.identifier.scopusqualityQ1
dc.identifier.startpage278en_US
dc.identifier.urihttps://doi.org/10.1016/j.jss.2009.02.009
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4721
dc.identifier.volume161en_US
dc.identifier.wosWOS:000277885300019
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofJournal Of Surgical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectesophagusen_US
dc.subjectgastricen_US
dc.subjectsmooth muscleen_US
dc.subjectcarbon dioxideen_US
dc.subjectpneumoperitoneumen_US
dc.titleEsophageal and Gastric Smooth Muscle Activity After Carbon Dioxide Pneumoperitoneumen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Esophageal and Gastric Smooth Muscle Activity After Carbon Dioxide Pneumoperitoneum.pdf
Boyut:
287.54 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu