Acute pancreatitis in Turkey: Results of a nationwide multicenter study

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dc.authoridTahtaci, Mustafa/0000-0003-4046-3715
dc.authoridSoyturk, Mujde/0000-0002-2646-639X
dc.authoridSAGLAM, Osman/0000-0003-0779-992X
dc.authoridtozlu, mukaddes/0000-0002-8534-8027
dc.authoridALTINTAS, ENGIN/0000-0003-0796-1456
dc.contributor.authorKoksal, Aydin Seref
dc.contributor.authorTozlu, Mukaddes
dc.contributor.authorSezgin, Orhan
dc.contributor.authorOguz, Dilek
dc.contributor.authorKalkan, Ismail Hakk
dc.contributor.authorAltntas, Engin
dc.contributor.authorYaras, Serkan
dc.date.accessioned2025-01-21T16:35:28Z
dc.date.available2025-01-21T16:35:28Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Acute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians ' compliance with international guidelines during its management. Methods: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria. Results: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically. Conclusions: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real -world practice. Mortality remains high in severe cases and physicians ' adherence to guidelines during management of the disease needs improvement in some aspects. (c) 2023 IAP and EPC. Published by Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.pan.2023.10.005
dc.identifier.endpage334
dc.identifier.issn1424-3903
dc.identifier.issn1424-3911
dc.identifier.issue3
dc.identifier.pmid37880021
dc.identifier.scopus2-s2.0-85174852169
dc.identifier.scopusqualityQ2
dc.identifier.startpage327
dc.identifier.urihttps://doi.org/10.1016/j.pan.2023.10.005
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24134
dc.identifier.volume24
dc.identifier.wosWOS:001230186300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofPancreatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectPancreatitis; Etiology; Morphology; Mortality; Guideline
dc.titleAcute pancreatitis in Turkey: Results of a nationwide multicenter study
dc.typeArticle

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