Olfactory bulb volume and olfactory sulcus depth in patients with Behcet's disease

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dc.contributor.authorDogan, A.
dc.contributor.authorMuluk, N. Bayar
dc.contributor.authorAsal, N.
dc.contributor.authorSahan, m H.
dc.contributor.authorInal, M.
dc.contributor.authorGunduz, O
dc.contributor.authorArikan, O. K.
dc.date.accessioned2020-06-25T18:23:56Z
dc.date.available2020-06-25T18:23:56Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionINAL, MIKAIL/0000-0003-0642-7913; , Ozgur/0000-0003-1021-5219
dc.description.abstractObjective To investigate olfactory bulb volume and olfactory sulcus depth in patients with Behcet's disease, using magnetic resonance imaging. Methods Cranial magnetic resonance imaging scans of 27 adults with Behcet's disease (10 males and 17 females) and 27 healthy controls were examined. Olfactory bulb volume and olfactory sulcus depth were measured on coronal, T2-weighted, spectral pre-saturation with inversion recovery sequences. Results Bilateral olfactory bulb volume and right-sided olfactory sulcus depth were significantly lower in the Behcet's disease group than in the control group (p < 0.05). Left-sided olfactory sulcus depth increased with Behcet's disease duration. In both groups, olfactory bulb volume was significantly higher in the left than the right side. There were no gender differences for olfactory bulb volume and olfactory sulcus depth. Positive correlations were determined between right- and left-sided olfactory bulb volume values and between right- and left-sided olfactory sulcus depth values. Conclusion Behcet's disease may decrease olfactory functions, related to lower olfactory bulb volume and olfactory sulcus depth. The affected vascular system and possibly damaged neural system, nasal mucosal lesions, and prolonged nasal mucociliary clearance time may cause olfactory dysfunction. Patient follow up is recommended, with magnetic resonance imaging examinations of the olfactory system if necessary.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1017/S0022215118002141
dc.identifier.endpage1092en_US
dc.identifier.issn0022-2151
dc.identifier.issn1748-5460
dc.identifier.issue12en_US
dc.identifier.pmid30558688
dc.identifier.startpage1088en_US
dc.identifier.urihttps://doi.org/10.1017/S0022215118002141
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7223
dc.identifier.volume132en_US
dc.identifier.wosWOS:000458491900009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofJournal Of Laryngology And Otology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet Diseaseen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectOlfaction Disordersen_US
dc.subjectOlfactory Bulben_US
dc.subjectOlfactory Sulcien_US
dc.titleOlfactory bulb volume and olfactory sulcus depth in patients with Behcet's diseaseen_US
dc.typeArticle

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