Maternal Low Quality Protein Diet Alters Plasma Amino Acid Concentrations of Weaning Rats

Basit Öğe Kaydı
dc.contributor.authorÇetin, Arzu Kabasakal
dc.contributor.authorDaşgın, Halil
dc.contributor.authorGüleç, Atila
dc.contributor.authorOnbaşılar, İlyas
dc.contributor.authorAkyol, Aslı
dc.date.accessioned2020-06-25T18:12:37Z
dc.date.available2020-06-25T18:12:37Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionAkyol, Asli/0000-0001-6301-6358
dc.description.abstractSeveral studies have indicated the influence of a maternal low protein diet on the fetus. However, the effect of a maternal low quality protein diet on fetal growth and development is largely unknown. Wistar rats (11 weeks old) were mated and maintained on either a chow diet with 20% casein (n = 6) as the control group (C), or a low quality protein diet with 20% wheat gluten (n = 7) as the experimental group (WG) through gestation and lactation. Maternal body weights were similar in both groups throughout the study. Birth weights were not influenced by maternal diet and offspring body weights during lactation were similar between the groups. Offspring's plasma amino acid profiles showed that plasma methionine, glutamine and lysine were significantly lower and aspartic acid, ornithine and glycine-proline were significantly higher in the WG. Plant based protein comprises an important part of protein intake in developing countries. It is well-known that these diets can be inadequate in terms of essential amino acids. The current study shows differential effects of a maternal low quality protein diet on the offspring's plasma amino acids. Future studies will examine further aspects of the influence of maternal low quality protein diets on fetal growth and development.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [114S812]en_US
dc.description.sponsorshipThe present study was funded by the Scientific and Technological Research Council of Turkey (TUBITAK), Number 114S812.en_US
dc.identifier.citationKabasakal Cetin A, Dasgin H, Gülec A, Onbasilar İ, Akyol A. Maternal Low Quality Protein Diet Alters Plasma Amino Acid Concentrations of Weaning Rats. Nutrients. 2015; 7(12):9847-9859. https://doi.org/10.3390/nu7125508en_US
dc.identifier.doi10.3390/nu7125508
dc.identifier.endpage9859en_US
dc.identifier.issn2072-6643
dc.identifier.issue12en_US
dc.identifier.pmid26633475
dc.identifier.scopus2-s2.0-84949595564
dc.identifier.scopusqualityQ1
dc.identifier.startpage9847en_US
dc.identifier.urihttps://doi.org/10.3390/nu7125508
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5984
dc.identifier.volume7en_US
dc.identifier.wosWOS:000367052200010
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpien_US
dc.relation.ispartofNutrients
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectfetal programmingen_US
dc.subjectlow quality proteinen_US
dc.subjectpregnancyen_US
dc.subjectratsen_US
dc.titleMaternal Low Quality Protein Diet Alters Plasma Amino Acid Concentrations of Weaning Ratsen_US
dc.typeArticle

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