The curative effect of some natural active compounds for liver cancer

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dc.authoridgokalp, faik/0000-0003-4363-3839
dc.contributor.authorGoekalp, Faik
dc.date.accessioned2025-01-21T16:44:57Z
dc.date.available2025-01-21T16:44:57Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractCancer is a disease that has become widespread recently and has been studied extensively. It is of great importance to find an active and effective treatment quickly due to the emergence of the disease and its spread to many tissues in the organism by metastasis. In this study, it is aimed to detect active and active substances that are highly effective on cancer cells in a short time by using docking scores, the accuracy of which has been proven by many studies. Today, many medicinal plants are being studied for therapeutic purposes. In this study, the activities of the prominent active substances in these medicinal plants were compared with the docking scores and the molecules with the highest inhibition effect on liver cancer receptors were determined. The data obtained in this study are of great importance in terms of guiding experimental studies by detecting active substances effective on liver cancer by preventing time and material loss. Considering the results obtained from this study, it can be concluded that Cucurbitacin I and Cucurbitacin E, Thymol, Piperine, and Carvacrol are very effective for the inhibition of liver cancer cell receptors.
dc.description.sponsorship[BAP-2016/016,-2017/019]; [2018/033]
dc.description.sponsorshipAcknowledgementsThe author is thankful to Kirikkale University for providing computers as projects (BAP-2016/016,-2017/019, 2018/033).
dc.identifier.doi10.1007/s12032-022-01933-3
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue1
dc.identifier.pmid36550238
dc.identifier.scopus2-s2.0-85144519262
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1007/s12032-022-01933-3
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25558
dc.identifier.volume40
dc.identifier.wosWOS:000901527500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc
dc.relation.ispartofMedical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectLiver cancer; Medicinal plant; Cucurbitacin E; Cucurbitacin I; Docking
dc.titleThe curative effect of some natural active compounds for liver cancer
dc.typeArticle

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