The effect of non-surgical periodontal treatment on gingival crevicular fluid periostin levels in patients with gingivitis and periodontitis

dc.contributor.authorArslan, Rana
dc.contributor.authorKarsiyaka Hendek, Meltem
dc.contributor.authorKisa, Ucler
dc.contributor.authorOlgun, Ebru
dc.date.accessioned2021-01-14T18:10:22Z
dc.date.available2021-01-14T18:10:22Z
dc.date.issued2020
dc.departmentKKÜ
dc.descriptionArslan, Rana/0000-0002-0962-2039
dc.description.abstractObjective The objective of the study was to evaluate the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) periostin levels in patients with gingivitis (G) and periodontitis (P). Subjects and methods A total of 90 subjects, 30 patients with P, 30 with G, and 30 periodontally healthy (H) subjects were included. Patients with periodontal disease received non-surgical periodontal treatment. GCF periostin levels were assessed at baseline, at the 6th week, and the 3rd month after treatment. Results It was found that GCF periostin level was the lowest in the H group (89.31[47.12] pg/30 sec), followed by the G group (132.82[145.14] pg/30 sec), and the highest in the P group (207.75[189.45] pg/30 sec). These differences were statistically significant between H and the other groups (p < .001). After treatment, GCF periostin levels significantly decreased at the 6th week and the 3rd month in the G group, at the 3rd month in the P group compared to baseline values (p < .05). Conclusion The results of this study suggest that GCF periostin plays a role as a reliable biological marker in the pathogenesis of periodontal disease and non-surgical periodontal treatment is effective in decreasing GCF periostin levels.en_US
dc.description.sponsorshipScientific Research Project Fund of Kirikkale UniversityKirikkale University [2017/43]en_US
dc.description.sponsorshipThe Scientific Research Project Fund of Kirikkale University, Grant/Award Number: 2017/43en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/odi.13664
dc.identifier.issn1354-523X
dc.identifier.issn1601-0825
dc.identifier.pmid33012041
dc.identifier.scopus2-s2.0-85093520663
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1111/odi.13664
dc.identifier.urihttps://hdl.handle.net/20.500.12587/12544
dc.identifier.wosWOS:000581136300001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWILEYen_US
dc.relation.ispartofORAL DISEASES
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe effect of non-surgical periodontal treatment on gingival crevicular fluid periostin levels in patients with gingivitis and periodontitisen_US
dc.typeArticle

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