Microalbuminuria in obstructive sleep apnea syndrome

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dc.contributor.authorBulcun, Emel
dc.contributor.authorEkici, Mehmet
dc.contributor.authorEkici, Aydanur
dc.contributor.authorÇimen, Dilay Ahat
dc.contributor.authorKısa, Üçler
dc.date.accessioned2020-06-25T18:12:37Z
dc.date.available2020-06-25T18:12:37Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810
dc.description.abstractObjectives Microalbuminuria is an important risk factor for cardiovascular diseases. Microalbuminuria may be seen due to intermittent hypoxemia in patients with obstructive sleep apnea syndrome (OSAS). In this study, we investigated the prevalence and relationship of microalbuminuria with clinical and physiological parameters in patients with OSAS. Method Ninety-eight patients with OSAS and 26 nonapneic snoring subjects upon polysomnography were included in this study. The urinary albumin-to-creatinine ratio (UACR) was calculated according to a previously described formula. The severity index of chronic diseases was evaluated by using the modified cumulative illness rating scale (MCIRS). Insulin resistance (IR) method was analyzed by homeostasis assessment model (HOMA-IR). Subjective sleepiness was assessed using the Epworth sleepiness scale (ESS). Results Body mass index (BMI), MCIRS, and UACR were higher in patients with OSAS than nonapneic snoring subjects. In linear regression model, there was a negative relationship between UACR and minimal O-2, and there was a significantly positive relationship between UACR and desaturation index. Conclusion Microalbuminuria may be seen in patients with OSAS, depending on the severity of disease and hypoxemia. Microalbuminuria in patients with OSAS should be examined in regular periods for risk of cardiovascular morbidity or mortality.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s11325-015-1136-8
dc.identifier.endpage1197en_US
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.issue4en_US
dc.identifier.pmid25778945
dc.identifier.scopus2-s2.0-84949092781
dc.identifier.scopusqualityQ1
dc.identifier.startpage1191en_US
dc.identifier.urihttps://doi.org/10.1007/s11325-015-1136-8
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5988
dc.identifier.volume19en_US
dc.identifier.wosWOS:000365744500011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofSleep And Breathing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObstructive sleep apnea syndromeen_US
dc.subjectMicroalbuminuriaen_US
dc.subjectIntermittent hypoxemiaen_US
dc.titleMicroalbuminuria in obstructive sleep apnea syndromeen_US
dc.typeArticle

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