Gender-related alerations in erythrocyte mechanical activities under desflurane or sevoflurane anesthesia

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dc.contributor.authorYerer, Muekerrem Betue
dc.contributor.authorAydogan, Sami
dc.contributor.authorComu, Faruk Metin
dc.date.accessioned2020-06-25T17:48:02Z
dc.date.available2020-06-25T17:48:02Z
dc.date.issued2008
dc.description14th Conference of the European-Society-for-Clinical-Hemorheology-and-Microcirculation -- JUN 27-30, 2007 -- Dresden, GERMANY
dc.descriptionYerer, Mukerrem B/0000-0002-4503-8032
dc.description.abstractAlterations in erythrocyte mechanical activities under the influence of anesthesia have been observed and discussed among the responsible factors for the deterioration of tissue and organ perfusion related to anesthetic procedures. 21 female and 17 male Swiss Albino rats were used. Female (f) and male ( m) rats were divided into 3 groups; control (f (n = 7); m (n = 5)), sevoflurane treated group (f (n = 7); m ( n = 5)), desflurane treated group ( f ( n = 7); m (n = 7)). 2% of sevoflurane or 6% desflurane were applied to the rats with inhalation in an adjustable cage for one hour. The deformability indexes of the erythrocytes were measured by a laser diffractometer (Myrenne Rheodyne SSD). Sevoflurane anesthesia has improved the deformability of erythrocytes in male rats (p < 0.05) whereas there were not any significant changes in female rats. Desflurane has improved the deformability of erythrocytes in both gender significantly (p < 0.05). Volatil anesthetic agents sevofluran and desflurane has improved the mechanical properties of the erythrocytes in male rats compared to their controls. However, these changes were not significant with sevoflurane in females. The results in male rats may be due to the effects of testosterone on the flexibility of the erythrocytes leading them to tolerate to the environmental changes. These results reveal that the inhalation anesthetics like sevoflurane and desflurane are appropriate anesthetics which can improve the deformability of erythrocytes during surgery.en_US
dc.description.sponsorshipEuropean Soc Clin Hemorheol & Microcirculaten_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.3233/CH-2008-1113
dc.identifier.endpage427en_US
dc.identifier.issn1386-0291
dc.identifier.issue1-4en_US
dc.identifier.pmid18503155
dc.identifier.scopus2-s2.0-47849101909
dc.identifier.scopusqualityQ2
dc.identifier.startpage423en_US
dc.identifier.urihttps://doi.org10.3233/CH-2008-1113
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4258
dc.identifier.volume39en_US
dc.identifier.wosWOS:000257384000054
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherIos Pressen_US
dc.relation.ispartofClinical Hemorheology And Microcirculation
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectsevofluraneen_US
dc.subjectdesfluraneen_US
dc.subjectanesthesiaen_US
dc.subjecterythrocyte deformabilityen_US
dc.subjectratsen_US
dc.titleGender-related alerations in erythrocyte mechanical activities under desflurane or sevoflurane anesthesiaen_US
dc.typeConference Object

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