Osteoclast-like giant cell tumour arising from the kidney in a dog

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Küçük Resim

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Akademiai Kiado

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

In this study, a case of osteoclast-like giant cell turnout arising from the kidney is reported in an eight-year-old female Anatolian Shepherd dog. Macroscopically, the tumorous mass covered the hilus of the left kidney. It was 26 x 22 x 12 cm in size and 3700 g in weight. Metastatic tumorous nodules, 0.5-2.0 cm in diameter, were found on the abdominal side of the diaphragm and in the lungs. Microscopically, numerous large osteoclast-like multinucleated giant cells and spindle-spheroidal-shaped cells were seen. Osteoblastic differentiation and osteoid matrix were noted in a few areas at the periphery of the tumour, near the connective tissue septa. The stroma of the tumour tissue was vascular, oedematous and loose. By immunoperoxidase staining, tumour cells showed immunoreactivity for vimentin but not for keratin and desmin, indicating that the tumour had mesenchymal origin. This is the first report in the literature on a malignant osteoclast-like giant cell turnout arising from a visceral organ in animals.

Açıklama

Guvenc, Tolga/0000-0003-1468-3415

Anahtar Kelimeler

dog, giant cell, kidney, osteoclast-like, tumour

Kaynak

Acta Veterinaria Hungarica

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

53

Sayı

2

Künye

closedAccess