Osteoclast-like giant cell tumour arising from the kidney in a dog

Basit Öğe Kaydı
dc.contributor.authorHaziroğlu, Rıfkı
dc.contributor.authorKul, Oğuz
dc.contributor.authorTunca, Recai
dc.contributor.authorGüvenç, Tolga
dc.date.accessioned2020-06-25T17:40:48Z
dc.date.available2020-06-25T17:40:48Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionGuvenc, Tolga/0000-0003-1468-3415
dc.description.abstractIn this study, a case of osteoclast-like giant cell turnout arising from the kidney is reported in an eight-year-old female Anatolian Shepherd dog. Macroscopically, the tumorous mass covered the hilus of the left kidney. It was 26 x 22 x 12 cm in size and 3700 g in weight. Metastatic tumorous nodules, 0.5-2.0 cm in diameter, were found on the abdominal side of the diaphragm and in the lungs. Microscopically, numerous large osteoclast-like multinucleated giant cells and spindle-spheroidal-shaped cells were seen. Osteoblastic differentiation and osteoid matrix were noted in a few areas at the periphery of the tumour, near the connective tissue septa. The stroma of the tumour tissue was vascular, oedematous and loose. By immunoperoxidase staining, tumour cells showed immunoreactivity for vimentin but not for keratin and desmin, indicating that the tumour had mesenchymal origin. This is the first report in the literature on a malignant osteoclast-like giant cell turnout arising from a visceral organ in animals.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1556/AVet.53.2005.2.7
dc.identifier.endpage230en_US
dc.identifier.issn0236-6290
dc.identifier.issue2en_US
dc.identifier.pmid15959980
dc.identifier.scopus2-s2.0-19944398480
dc.identifier.scopusqualityQ2
dc.identifier.startpage225en_US
dc.identifier.urihttps://doi.org/10.1556/AVet.53.2005.2.7
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3556
dc.identifier.volume53en_US
dc.identifier.wosWOS:000229406800007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAkademiai Kiadoen_US
dc.relation.ispartofActa Veterinaria Hungarica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdogen_US
dc.subjectgiant cellen_US
dc.subjectkidneyen_US
dc.subjectosteoclast-likeen_US
dc.subjecttumouren_US
dc.titleOsteoclast-like giant cell tumour arising from the kidney in a dogen_US
dc.typeArticle

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