The possible association of Chlamydia pneumoniae infection with nasal polyps

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dc.contributor.authorApan, Teoman Zafer
dc.contributor.authorAlpay, Dogan
dc.contributor.authorAlpay, Yeşim
dc.date.accessioned2020-06-25T17:44:04Z
dc.date.available2020-06-25T17:44:04Z
dc.date.issued2007
dc.description.abstractThe objective of this study was to investigate the possible etiologic role of Chlamydia pneumoniae infection in nasal polyps. This prospective clinical study was undertaken enrolling 30 patients with nasal polyps, and 30 age and sex-matched control subjects from whom epithelial material was obtained during endoscopic surgery. IgG specific ELISA was used to determine seropositivity, and indirect immunoflorescence to determine C. pneumoniae in the biopsy material. C pneumoniae specific IgG antibodies were found to be positive in 16 (53.3%) of the patients with nasal polyps, and 9 (22%) of the control subjects (P = 0.065). Indirect immunofluorescence results indicate that there was a significant difference between groups; 16 (53.3%) patients in the study group and,8 (26.6%) patients in the control group were found to be positive (P = 0.034). We found no correlation with cigarette smoking. Our results indicated that Chlamydia pneumoniae is possibly associated with the presence of nasal polyps. However, these results remain to be confirmed with further studies using other techniques, and the underlying mechanism should be defined.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s00405-006-0140-9
dc.identifier.endpage31en_US
dc.identifier.issn0937-4477
dc.identifier.issn1434-4726
dc.identifier.issue1en_US
dc.identifier.pmid16902779
dc.identifier.scopus2-s2.0-33845411571
dc.identifier.scopusqualityQ1
dc.identifier.startpage27en_US
dc.identifier.urihttps://doi.org10.1007/s00405-006-0140-9
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3996
dc.identifier.volume264en_US
dc.identifier.wosWOS:000243347400005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChlamydiaen_US
dc.subjectinfectionen_US
dc.subjectnasal polypsen_US
dc.subjectsmokingen_US
dc.titleThe possible association of Chlamydia pneumoniae infection with nasal polypsen_US
dc.typeArticle

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