Evaluation of gallbladder motility in patients with irritable bowel syndrome
Yükleniyor...
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
E M H Swiss Medical Publishers Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Abnormalities involving smooth muscle function in different systems of the body have been reported in irritable bowel syndrome (IBS). There are a few studies on gallbladder function in this disorder with conflicting results. Objectives: To investigate the motility of gallbladder in patients with IBS. Patients and methods: Forty-eight patients (15 male and 3 3 female) with IBS and 48 healthy volunteers (15 male and 3 3 female) were included into the study. Thirty-four patients (70.8%) had constipation predominant and 14 patients (29.2%) had diarrhoea predominant type of IBS. Fasting and postprandial gallbladder volumes were studied using real time ultrasonography and ejection fraction (EF) of gallbladder was calculated. Results: While fasting gallbladder volume (FGV) was similar between IBS and control groups (18.0 +/- 4.0 ml vs. 17.8 +/- 4.9 ml, p > 0.05), postprandial gallbladder volume (PGV) was lower in IBS group than in the control group (5.5 +/- 1.4 ml vs. 6.2 +/- 1.9 ml, p = 0.03). Accordingly, the mean EF of gallbladders was found to be higher in IBS group than in the control group (69.1% vs. 64.1%, p = 0.0001). There were no difference in FGV, PGV and EF of gallbladders between constipation predominant and diarrhoea predominant IBS patients (P > 0.05). Conclusion: The results of this study indicated that IBS patients have increased emptying of gallbladder compared to healthy subjects.
Açıklama
Anahtar Kelimeler
irritable bowel syndrome, gallbladder, motility
Kaynak
Swiss Medical Weekly
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
135
Sayı
27-28
Künye
Guliter S, Yakaryilmaz F, Keles H. Evaluation of gallbladder motility in patients with irritable bowel syndrome. Swiss Med Wkly [Internet]. 2005 Jul. 16 [cited 2024 Aug. 5];135(2728):407-11. Available from: https://smw.ch/index.php/smw/article/view/512
