Evaluation of gallbladder volume and motility in non-insulin-dependent diabetes mellitus patients using real-time ultrasonography

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dc.contributor.authorGuliter, S.
dc.contributor.authorYilmaz, S.
dc.contributor.authorKarakan, T.
dc.date.accessioned2020-06-25T17:35:17Z
dc.date.available2020-06-25T17:35:17Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.descriptionkarakan, tarkan/0000-0003-1561-8789;
dc.description.abstractAims: The prevalence of cholelithiasis is 2 to 3 times higher in patients with diabetes mellitus than in the normal population, especially in a group of patients with non-insulin-dependent diabetes mellitus (NIDDM). We investigated the pathogenesis of this increased prevalence by ultrasonography with a brief comparison of demographic features. Materials and Methods: The study group was consisted of NIDDM patients (41 males and 47 females, mean age 53.5 +/- 11 years), and the control group included healthy volunteers (33 males and 34 females, mean age 50.3 +/- 18 years). All patients were investigated after 12 hours of fasting and 30 minutes after a standard test meal. Pre-meal and post-meal gallbladder volumes were used for calculation of the ejection fraction of the gallbladder and fasting gallbladder volume. Results: In the study group, there was no correlation between the fasting gallbladder volume and age, parity, and body mass index. However, fasting gallbladder volume and duration of diabetes mellitus showed significant correlation (r = 0.212, P < 0.05). The mean ejection fraction of gallbladders in the study group was 48.48%, whereas that of the control group was 56.32%. There was a significant reduction of ejection fraction in the study group (P = 0.003). Conclusion: Our study indicated that there were an increased fasting gallbladder volume and impaired ejection fraction in NIDDM patients. This may be the initiator of bile stasis in the gallbladder and subsequent cholesterol crystal and stone formation.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage291en_US
dc.identifier.issn0192-0790
dc.identifier.issue4en_US
dc.identifier.pmid14506384
dc.identifier.scopus2-s2.0-18744427271
dc.identifier.scopusqualityQ2
dc.identifier.startpage288en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3081
dc.identifier.volume37en_US
dc.identifier.wosWOS:000185458400005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Clinical Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEvaluation of gallbladder volume and motility in non-insulin-dependent diabetes mellitus patients using real-time ultrasonographyen_US
dc.typeArticle

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