Heart Rate Variability in Neonates with Hypoxic Ischemic Encephalopathy
Yükleniyor...
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
All India Inst Medical Sciences
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective To evaluate the changes in heart rate variability (HRV) in newborns with hypoxic-ischemic encephalopathy (HIE). Methods Twenty-two newborns (14 boys, 8 girls) with moderate or severe HIE and 24 term neonates with similar gestational and postnatal age for control were included in this study. Normalized low and high frequency components of HRV and their ratio were evaluated for 24-h in newborns with HIE and control subjects. Results The newborns with hypoxic-ischemic encephalopathy had significantly lower normalized low frequency (LFn) and low frequency (LF) / high frequency (HF) values and higher normalized high frequency (HFn) values when compared with the control babies. In addition, when the cases with severe HIE are compared with those of moderate HIE, decreased LFn, LF/HF values and also increased HFn values were present in the severe cases. Conclusions HIE is associated with reduced sympathetic nervous system activity, and increased parasympathetic nervous system activity and these activities also correlate with the severity of the disease.
Açıklama
Albayrak, Meryem/0000-0003-2711-5150
Anahtar Kelimeler
Hypoxic ischemic encephalopathy, Autonomic nervous system, Heart rate variability, Parasympathetic activity, Sympathetic activity
Kaynak
Indian Journal Of Pediatrics
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
79
Sayı
11
Künye
closedAccess
