Heart Rate Variability in Neonates with Hypoxic Ischemic Encephalopathy

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dc.contributor.authorAliefendioglu, Didem
dc.contributor.authorDogru, Tolga
dc.contributor.authorAlbayrak, Meryem
dc.contributor.authorDibekMisirlioglu, Emine
dc.contributor.authorSanli, Cihat
dc.date.accessioned2020-06-25T17:52:33Z
dc.date.available2020-06-25T17:52:33Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.descriptionAlbayrak, Meryem/0000-0003-2711-5150
dc.description.abstractObjective To evaluate the changes in heart rate variability (HRV) in newborns with hypoxic-ischemic encephalopathy (HIE). Methods Twenty-two newborns (14 boys, 8 girls) with moderate or severe HIE and 24 term neonates with similar gestational and postnatal age for control were included in this study. Normalized low and high frequency components of HRV and their ratio were evaluated for 24-h in newborns with HIE and control subjects. Results The newborns with hypoxic-ischemic encephalopathy had significantly lower normalized low frequency (LFn) and low frequency (LF) / high frequency (HF) values and higher normalized high frequency (HFn) values when compared with the control babies. In addition, when the cases with severe HIE are compared with those of moderate HIE, decreased LFn, LF/HF values and also increased HFn values were present in the severe cases. Conclusions HIE is associated with reduced sympathetic nervous system activity, and increased parasympathetic nervous system activity and these activities also correlate with the severity of the disease.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s12098-012-0703-2
dc.identifier.endpage1472en_US
dc.identifier.issn0019-5456
dc.identifier.issue11en_US
dc.identifier.pmid22359196
dc.identifier.scopus2-s2.0-84871306719
dc.identifier.scopusqualityQ1
dc.identifier.startpage1468en_US
dc.identifier.urihttps://doi.org/10.1007/s12098-012-0703-2
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5174
dc.identifier.volume79en_US
dc.identifier.wosWOS:000310974500005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAll India Inst Medical Sciencesen_US
dc.relation.ispartofIndian Journal Of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHypoxic ischemic encephalopathyen_US
dc.subjectAutonomic nervous systemen_US
dc.subjectHeart rate variabilityen_US
dc.subjectParasympathetic activityen_US
dc.subjectSympathetic activityen_US
dc.titleHeart Rate Variability in Neonates with Hypoxic Ischemic Encephalopathyen_US
dc.typeArticle

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