Bullous scabies, the light shed on etiopathogenesis and treatment: report of five paediatric cases

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Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Termedia Publishing House Ltd

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Introduction: Bullous scabies (BS) is an infrequent and atypical presentation of scabies, with a predilection for el- derly males. The mechanism of BS is not fully understood; superinfection, friction due to pruritus, autoeczemation, direct injury from mite's lytic enzymes, cross-reactivity of scabies protein with basal membrane zone antigens are considered to be possible reasons. Aim: To define clinical features of paediatric BS cases, which is an extremely rare subtype of scabies. Material and methods: This is a retrospective study of paediatric BS cases seen at two tertiary care centres. Previ- ously described bacterial culture, antibiogram and follow-up records were investigated retrospectively. Confirmed scabies cases, according to the International Alliance for the Control of Scabies (IACS) with bullae were included. All cases were treated with 10% sulfur ointment for 3 consecutive days, two cycles. Households of cases were also treated simultaneously. Systemic antibiotics were added to patients with elevated acute phase reactants according to the antibiogram results. Informed consent was obtained from patients' parents. Results: Five BS cases were included. Three cases were male, two cases were female. Four cases had staphylococcus aureus, one had group-A beta haemolytic streptococcus positive bullae culture. All cases achieved a rapid complete resolution of symptoms after topical 10% sulfur ointment. Conclusions: Paediatric BS is an extremely rare entity of scabies. Bacterial superinfection plays a key role in bullae formation. 10% sulfur ointment is a highly effective treatment option for paediatric BS.

Açıklama

Anahtar Kelimeler

bullous scabies; haemorrhagic bullae; scabies; paediatrics; bacterial superinfection

Kaynak

Postepy Dermatologii I Alergologii

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

40

Sayı

3

Künye