Bullous scabies, the light shed on etiopathogenesis and treatment: report of five paediatric cases

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dc.authoridGündüz, Özgür/0000-0003-1021-5219
dc.contributor.authorArslan, Hakan
dc.contributor.authorGündüz, Özgür
dc.date.accessioned2025-01-21T16:36:16Z
dc.date.available2025-01-21T16:36:16Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIntroduction: Bullous scabies (BS) is an infrequent and atypical presentation of scabies, with a predilection for el- derly males. The mechanism of BS is not fully understood; superinfection, friction due to pruritus, autoeczemation, direct injury from mite's lytic enzymes, cross-reactivity of scabies protein with basal membrane zone antigens are considered to be possible reasons. Aim: To define clinical features of paediatric BS cases, which is an extremely rare subtype of scabies. Material and methods: This is a retrospective study of paediatric BS cases seen at two tertiary care centres. Previ- ously described bacterial culture, antibiogram and follow-up records were investigated retrospectively. Confirmed scabies cases, according to the International Alliance for the Control of Scabies (IACS) with bullae were included. All cases were treated with 10% sulfur ointment for 3 consecutive days, two cycles. Households of cases were also treated simultaneously. Systemic antibiotics were added to patients with elevated acute phase reactants according to the antibiogram results. Informed consent was obtained from patients' parents. Results: Five BS cases were included. Three cases were male, two cases were female. Four cases had staphylococcus aureus, one had group-A beta haemolytic streptococcus positive bullae culture. All cases achieved a rapid complete resolution of symptoms after topical 10% sulfur ointment. Conclusions: Paediatric BS is an extremely rare entity of scabies. Bacterial superinfection plays a key role in bullae formation. 10% sulfur ointment is a highly effective treatment option for paediatric BS.
dc.identifier.doi10.5114/ada.2023.128976
dc.identifier.endpage436
dc.identifier.issn1642-395X
dc.identifier.issn2299-0046
dc.identifier.issue3
dc.identifier.pmid37545831
dc.identifier.scopus2-s2.0-85167913690
dc.identifier.scopusqualityQ2
dc.identifier.startpage432
dc.identifier.urihttps://doi.org/10.5114/ada.2023.128976
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24288
dc.identifier.volume40
dc.identifier.wosWOS:001033632600017
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltd
dc.relation.ispartofPostepy Dermatologii I Alergologii
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectbullous scabies; haemorrhagic bullae; scabies; paediatrics; bacterial superinfection
dc.titleBullous scabies, the light shed on etiopathogenesis and treatment: report of five paediatric cases
dc.typeArticle

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