Total and lipid bound sialic acid levels in patients with polycystic ovary syndrome

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dc.contributor.authorÖzcan A.
dc.contributor.authorYücel A.
dc.contributor.authorNoyan V.
dc.contributor.authorSağsöz N.
dc.contributor.authorÇağlayan O.
dc.date.accessioned2020-06-25T15:17:16Z
dc.date.available2020-06-25T15:17:16Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: To evaluate serum total and lipid bound sialic acid (TSA&LBSA) levels in patients with polycystic ovary syndrome (PCOS). Material and Methods: Forty women with PCOS and 35 healthy controls were enrolled in the study. Serum TSA, LBSA, follicle stimulating hormone, lutenizing hormone, estradiol, thyroid stimulating hormone, prolactin, dehydroepiandrosterone sulphate, androstenedione, free testosterone, total testosterone, 17-OH progesterone, sex hormone binding globulin, cortisol, total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein were measured in each subject. Insulin resistance was estimated by fasting insulin level, fasting glucose: insulin ratio and 75-g glucose tolerance test for 2 hours. Results: Serum TSA levels were not significantly different between the groups. Serum LBSA levels were higher in patients with PCOS compared to the control group. TSA was correlated with androstenedione and HOMA-IR in the PCOS group. Positive correlations were found between LBSA and dehydroepiandrosterone sulphate in patients with PCOS. After correction for BMI, the only existing significant correlation was between LBSA and follicle stimulating hormone. Conclusion: Serum LBSA levels, which has previously been found to be higher in cardiovascular diseases and diabetes mellitus, are elevated in PCOS. © 2012 by the Turkish-German Gynecological Education and Research Foundation.en_US
dc.identifier.citationÖzcan, A., Yücel, A., Noyan, V., Sağsöz, N., Çağlayan, O. (2012). Total and lipid bound sialic acid levels in patients with polycystic ovary syndrome. Journal of the Turkish-German Gynecological Association, 13(2), 79 - 84.en_US
dc.identifier.doi10.5152/jtgga.2012.08
dc.identifier.endpage84en_US
dc.identifier.issn13090399
dc.identifier.issue2en_US
dc.identifier.pmid24592013
dc.identifier.scopus2-s2.0-84862677128
dc.identifier.scopusqualityQ3
dc.identifier.startpage79en_US
dc.identifier.trdizinid139496
dc.identifier.urihttps://doi.org/10.5152/jtgga.2012.08
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2258
dc.identifier.volume13en_US
dc.identifier.wosWOS:000420649900002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAVESen_US
dc.relation.ispartofJournal of the Turkish German Gynecology Association
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLipid bound sialic aciden_US
dc.subjectPolycystic ovary syndromeen_US
dc.subjectRisken_US
dc.subjectTotal sialic aciden_US
dc.titleTotal and lipid bound sialic acid levels in patients with polycystic ovary syndromeen_US
dc.title.alternativePolikistik over sendromlu hastalarda total ve lipid bağlı sialik asit seviyelerien_US
dc.typeArticle

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