Antibacterial activity of fluoride varnishes containing different agents in children with severe early childhood caries: a randomised controlled trial
Yükleniyor...
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SPRINGER HEIDELBERG
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objectives The aim of this study was to compare the antibacterial activity of fluoride varnishes containing different agents in children with severe early childhood caries (S-ECC). Materials and methods The study was conducted in 92 children with S-ECC. Patients who completed dental treatment under general anaesthesia were included in the study. Patients were divided randomly into four groups: 5% sodium fluoride (SF) control group (n = 23), 5% SF with tricalcium phosphate (TCP) (n = 23), 5% SF with xylitol-coated calcium and phosphate (CXP) (n = 23) and 5% SF with casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (n = 23). Saliva mutans streptococci (MS) and lactobacilli (LB) levels were evaluated by taking saliva samples at baseline (T-0), 1 month (T-1) and 3 months (T-2) after treatment. Results All groups showed a significant decrease in MS and LB levels at T-1 (P < 0.05) except the CXP group. Only the TCP group exhibited significantly decrease MS and LB levels indicating less than 10(5) CFU at both T-1 and T-2 compared with the other groups (P < 0.05). Conclusion Fluoride varnish with TCP provided significantly more reduction in MS and LB levels than other fluoride varnishes. Clinical Trials registration number NCT03625310
Açıklama
Anahtar Kelimeler
Bacteria, Children, Dental caries, Fluoride varnishes
Kaynak
CLINICAL ORAL INVESTIGATIONS
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
24
Sayı
6
Künye
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