Investigation of OH-proline contents of hernia sacs in children and comparison with adults

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dc.contributor.authorÇağlayan, Fatma
dc.contributor.authorÇağlayan, Osman
dc.contributor.authorÇakmak, Murat
dc.contributor.authorSaygun, Oral
dc.contributor.authorSomuncu, Salih
dc.contributor.authorUlusoy, Sevgi
dc.contributor.authorAkman, H
dc.date.accessioned2020-06-25T17:40:28Z
dc.date.available2020-06-25T17:40:28Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurpose: One of the factors suggested to be causative in hernia formation is defective collagen metabolism. In this study, we investigated whether there is any relationship between the collagen contents of indirect hernial sacs and certain demographic and anatomic parameters. Methods: Hernial sac hydroxyproline levels were measured in 100 pediatric and 23 adult indirect inguinal hernia cases as indicators of collagen concentrations. Hydroxyproline levels were compared between boys and girls, right and left sided hernias, unilateral and bilateral cases, children and adults. Whether there was any relationship between patient age and hydroxyproline level was also investigated. Results: No difference was found between males and females (p > 0.05), right and left sided hernias (p > 0.05) or unilateral and bilateral cases (p > 0.05). Hydroxyproline levels of adults were found to be significantly higher than those of children (p = 0.000). There was also a positive correlation between age and hydroxyproline levels of boys (r = 0.285, p = 0.023). Conclusion: Although a relationship between direct inguinal hernia and collagen structure has been shown by some investigators, we were unable to point to any significant findings which would indicate such a relationship in indirect inguinal hernia cases. Further studies on hydroxyproline levels in peritoneal samples will be necessary to understand the role of peritoneal hydroxyproline levels in hernia formation.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1055/s-2005-865810
dc.identifier.endpage261en_US
dc.identifier.issn0939-7248
dc.identifier.issue4en_US
dc.identifier.pmid16163591
dc.identifier.scopus2-s2.0-25144524984
dc.identifier.scopusqualityQ1
dc.identifier.startpage258en_US
dc.identifier.urihttps://doi.org/10.1055/s-2005-865810
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3452
dc.identifier.volume15en_US
dc.identifier.wosWOS:000231963500005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofEuropean Journal Of Pediatric Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectindirect inguinal herniaen_US
dc.subjectcollagenen_US
dc.subjecthydroxyprolineen_US
dc.titleInvestigation of OH-proline contents of hernia sacs in children and comparison with adultsen_US
dc.typeArticle

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