Anti-inflammatory activity of Anthemis tricolor Boiss
Yükleniyor...
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Termedia Publishing House Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemis species such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties. Aim: Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts. Material and methods: Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolor Bois showed significantly reduced erythema compared to the negative control. Results: Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect. Conclusions: This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a_result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity.
Açıklama
Anahtar Kelimeler
Anthemis tricolor, anti-inflammatory, n-hexane, sesquiterpene, minimal erythema dose
Kaynak
Postepy Dermatologii I Alergologii
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
36
Sayı
6
Künye
Demirkan S, Özçınar Ö, Kıvçak B. Anti-inflammatory activity of Anthemis tricolor Boiss. Postepy Dermatol Alergol. 2019 Dec;36(6):677-680.
