Anti-inflammatory activity of Anthemis tricolor Boiss

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dc.contributor.authorDemirkan, Serkan
dc.contributor.authorOzcinar, Ozge
dc.contributor.authorKivcak, Bijen
dc.date.accessioned2020-06-25T18:34:24Z
dc.date.available2020-06-25T18:34:24Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIntroduction: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemis species such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties. Aim: Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts. Material and methods: Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolor Bois showed significantly reduced erythema compared to the negative control. Results: Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect. Conclusions: This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a_result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity.en_US
dc.identifier.citationDemirkan S, Özçınar Ö, Kıvçak B. Anti-inflammatory activity of Anthemis tricolor Boiss. Postepy Dermatol Alergol. 2019 Dec;36(6):677-680.en_US
dc.identifier.doi10.5114/ada.2019.91417
dc.identifier.endpage680en_US
dc.identifier.issn1642-395X
dc.identifier.issue6en_US
dc.identifier.pmid31997994
dc.identifier.scopus2-s2.0-85078158113
dc.identifier.scopusqualityQ2
dc.identifier.startpage677en_US
dc.identifier.urihttps://doi.org/10.5114/ada.2019.91417
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7894
dc.identifier.volume36en_US
dc.identifier.wosWOS:000506827300006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofPostepy Dermatologii I Alergologii
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnthemis tricoloren_US
dc.subjectanti-inflammatoryen_US
dc.subjectn-hexaneen_US
dc.subjectsesquiterpeneen_US
dc.subjectminimal erythema doseen_US
dc.titleAnti-inflammatory activity of Anthemis tricolor Boissen_US
dc.typeArticle

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