Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds
Yükleniyor...
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Informa Healthcare
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Bovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I was no longer expressed at day 14. The DNA content increased until day 8 and began declining, indicating cell detachment. The GAG content increased during the first 12 days. The percentage of round and collagen type II immunoreactive cells increased over the time. Catechin has some protective properties on chondrocytes seeded on the alginate-chitosan scaffolds during the first 12 days by means of DNA and chondrocyte morphology (p < 0.05).
Açıklama
DINCEL, Gungor Cagdas/0000-0002-6985-3197
Anahtar Kelimeler
Alginate, catechin, chitosan, chondrocyte, scaffold
Kaynak
Artificial Cells Nanomedicine And Biotechnology
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
41
Sayı
4
Künye
Mustafa Türk, Siyami Karahan, Miyase Çinar, Şebnem Küçük & Güngör Çagdaş Dinçel (2013) Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds, Artificial Cells, Nanomedicine, and Biotechnology, 41:4, 240-248.
