Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds

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dc.contributor.authorTurk, Mustafa
dc.contributor.authorKarahan, Siyami
dc.contributor.authorCinar, Miyase
dc.contributor.authorKucuk, Sebnem
dc.contributor.authorDincel, Gungor Cagdas
dc.date.accessioned2020-06-25T18:07:07Z
dc.date.available2020-06-25T18:07:07Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.descriptionDINCEL, Gungor Cagdas/0000-0002-6985-3197
dc.description.abstractBovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I was no longer expressed at day 14. The DNA content increased until day 8 and began declining, indicating cell detachment. The GAG content increased during the first 12 days. The percentage of round and collagen type II immunoreactive cells increased over the time. Catechin has some protective properties on chondrocytes seeded on the alginate-chitosan scaffolds during the first 12 days by means of DNA and chondrocyte morphology (p < 0.05).en_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey (Tubitak Project)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [107O681]en_US
dc.description.sponsorshipThis study was conducted by a grant provided by the Scientific and Technical Research Council of Turkey (Tubitak Project no: 107O681).en_US
dc.identifier.citationMustafa Türk, Siyami Karahan, Miyase Çinar, Şebnem Küçük & Güngör Çagdaş Dinçel (2013) Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds, Artificial Cells, Nanomedicine, and Biotechnology, 41:4, 240-248.en_US
dc.identifier.doi10.3109/10731199.2012.718283
dc.identifier.endpage248en_US
dc.identifier.issn2169-1401
dc.identifier.issue4en_US
dc.identifier.pmid22992139
dc.identifier.scopus2-s2.0-84880861543
dc.identifier.scopusqualityQ1
dc.identifier.startpage240en_US
dc.identifier.urihttps://doi.org/10.3109/10731199.2012.718283
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5481
dc.identifier.volume41en_US
dc.identifier.wosWOS:000322338300003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInforma Healthcareen_US
dc.relation.ispartofArtificial Cells Nanomedicine And Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlginateen_US
dc.subjectcatechinen_US
dc.subjectchitosanen_US
dc.subjectchondrocyteen_US
dc.subjectscaffolden_US
dc.titleCharacterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffoldsen_US
dc.typeArticle

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