Response to vaccination against hepatitis B in patients with Behcet's disease

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dc.contributor.authorErkek, Emel
dc.contributor.authorAyaşlıoğlu, Ergin
dc.contributor.authorErkek, Ayhan Bülent
dc.contributor.authorKurtipek, Gülcan Saylam
dc.contributor.authorBağcı, Yeter
dc.date.accessioned2020-06-25T17:40:23Z
dc.date.available2020-06-25T17:40:23Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionERKEK, BULENT/0000-0002-9041-341X
dc.description.abstractBackground and Aims: Hepatitis B virus infection is an important public health problem in Turkey. Although hepatitis B vaccination is regarded as safe and effective for the general population, recommendations for hepatitis B immunization in patients with Behcet's disease are not clear. The aim of the present study was to elucidate the response of patients with Behcet's disease to hepatitis B vaccination and to determine whether hepatitis B vaccination has any adverse effects on the course of the disease. Methods: Thirteen patients with Behcet's disease and 15 healthy individuals were enrolled into a prospective study. All subjects received the 3-dose series of routine hepatitis B vaccine. Anti-hepatitis B surface response was evaluated 1-3 months after the third dose of vaccine. Results: The responder rates for patient and control groups were 12/13 (92.8%) and 14/15 (93.8%), respectively. Statistical analysis showed no significant difference between the two groups in terms of both the responder rates and mean antibody titers. Conclusions: These preliminary findings might suggest that the majority of patients with Behcet's disease develop protective antibody response after hepatitis B vaccination and that the immune response against hepatitis B surface antigen is adequate, efficient and intact. (C) 2005 Blackwell Publishing Asia Pty Ltd.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/j.1440-1746.2005.03903.x
dc.identifier.endpage1511en_US
dc.identifier.issn0815-9319
dc.identifier.issue10en_US
dc.identifier.pmid16174066
dc.identifier.scopus2-s2.0-33644674413
dc.identifier.scopusqualityQ1
dc.identifier.startpage1508en_US
dc.identifier.urihttps://doi.org/10.1111/j.1440-1746.2005.03903.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3420
dc.identifier.volume20en_US
dc.identifier.wosWOS:000231611700006
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofJournal Of Gastroenterology And Hepatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjecthepatitis B infectionen_US
dc.subjecthepatitis B vaccinationen_US
dc.subjectresponseen_US
dc.subjectside-effectsen_US
dc.titleResponse to vaccination against hepatitis B in patients with Behcet's diseaseen_US
dc.typeArticle

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