Effects of exposure to new inhalational anesthetics on spermatogenesis and sperm morphology in rabbits
Yükleniyor...
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The effects of chronic exposure to new inhalation anesthetics (sevoflurane and isoflurane) on spermatogenesis and sperm morphology were examined in 23 rabbits, randomly divided in 3 groups. Rabbits received 20 exposure hours (four hours/day x 5 days), as follows: group I: 2.3% (1.2 MAC) sevoflurane+2L/min oxygen, group II: 1.3% (1.2 MAC) isoflurane+2L/min oxygen, and group III (control): 2L/min oxygen. Semen was collected on the 12th, 19th, 26th, 33rd, and 41st days of exposure. Sperm concentration, motility and morphological changes were evaluated. On the 41st day, testicular biopsies were taken and observed with light microscopy. Sperm concentration and motility significantly decreased in the sevoflurane and the isoflurane groups, compared to control. There were no significant changes in the control group. It is concluded that chronic exposure to the new inhalational anesthetics had negative effects on spermatogenesis and sperm morphology.
Açıklama
CINCIK, Mehmet/0000-0002-0717-1756
Anahtar Kelimeler
concentration, inhalational anesthetics, isoflurane, motility, sevoflurane, sperm, spermatogenesis, testis
Kaynak
Archives Of Andrology
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
51
Sayı
4
Künye
closedAccess
