Effects of exposure to new inhalational anesthetics on spermatogenesis and sperm morphology in rabbits

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dc.contributor.authorCeyhan, A.
dc.contributor.authorCincik, M.
dc.contributor.authorBedir, S.
dc.contributor.authorÜstün, H.
dc.contributor.authorDağlı, G.
dc.contributor.authorKalender, H.
dc.date.accessioned2020-06-25T17:40:32Z
dc.date.available2020-06-25T17:40:32Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionCINCIK, Mehmet/0000-0002-0717-1756
dc.description.abstractThe effects of chronic exposure to new inhalation anesthetics (sevoflurane and isoflurane) on spermatogenesis and sperm morphology were examined in 23 rabbits, randomly divided in 3 groups. Rabbits received 20 exposure hours (four hours/day x 5 days), as follows: group I: 2.3% (1.2 MAC) sevoflurane+2L/min oxygen, group II: 1.3% (1.2 MAC) isoflurane+2L/min oxygen, and group III (control): 2L/min oxygen. Semen was collected on the 12th, 19th, 26th, 33rd, and 41st days of exposure. Sperm concentration, motility and morphological changes were evaluated. On the 41st day, testicular biopsies were taken and observed with light microscopy. Sperm concentration and motility significantly decreased in the sevoflurane and the isoflurane groups, compared to control. There were no significant changes in the control group. It is concluded that chronic exposure to the new inhalational anesthetics had negative effects on spermatogenesis and sperm morphology.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1080/0148501090919675
dc.identifier.endpage315en_US
dc.identifier.issn0148-5016
dc.identifier.issue4en_US
dc.identifier.pmid16036639
dc.identifier.scopus2-s2.0-79961146272
dc.identifier.scopusqualityN/A
dc.identifier.startpage305en_US
dc.identifier.urihttps://doi.org/10.1080/0148501090919675
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3472
dc.identifier.volume51en_US
dc.identifier.wosWOS:000230455900008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofArchives Of Andrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectconcentrationen_US
dc.subjectinhalational anestheticsen_US
dc.subjectisofluraneen_US
dc.subjectmotilityen_US
dc.subjectsevofluraneen_US
dc.subjectspermen_US
dc.subjectspermatogenesisen_US
dc.subjecttestisen_US
dc.titleEffects of exposure to new inhalational anesthetics on spermatogenesis and sperm morphology in rabbitsen_US
dc.typeArticle

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