Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Natl Inst Infectious Diseases
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal disease which is endemic to Turkey. We aimed to investigate the procalcitonin levels and their prognostic value over fatality in CCHF patients. The sera were harvested from patients who were diagnosed with CCHF within the first 2 days of the onset of their symptoms. The patients were divided into 2 groups according to their survival status: fatal or non-fatal. The biochemical and hematological parameters were studied in the Biochemistry Laboratory of Sorgun City Hospital. The sera were stored at -80 degrees C until testing for procalcitonin, and the procalcitonin levels were assayed by ELISA at the Biochemistry Laboratory of Kirikkale University. Forty- eight patients were included in the study, with 8 and 40 patients in the fatal and non-fatal groups, respectively. While the procalcitonin level was high in all patients in the fatal group, the same was observed in 30 patients in the non-fatal group (75%). The mean value of procalcitonin was 1.12 ng/ml in the fatal group and was 0.21 ng/ml in the non-fatal group (P = 0.003). According to the results of our study, the procalcitonin levels in the first 2 days of the onset of the symptoms might be helpful for predicting fatality in CCHF patients.
Açıklama
KISA, Ucler/0000-0002-8131-6810
Anahtar Kelimeler
Kaynak
Japanese Journal Of Infectious Diseases
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
68
Sayı
6
Künye
Gul, S., Ozturk, D. B., Kisa, U., Kacmaz, B., & Yesilyurt, M. (2015). Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients. Japanese journal of infectious diseases, 68(6), 511–513. https://doi.org/10.7883/yoken.JJID.2014.485
