The relationship between serum adiponectin level and anthropometry, bone mass, osteoporotic fracture risk in postmenopausal women
Yükleniyor...
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Joint Diseases Foundation
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: The aim of the present study was to evaluate the possible correlation between bone mass and serum adiponectin levels, and the correlation between adiponectin levels and osteoporotic fracture risk in a prospective clinical trial. Patients and methods: Postmenopausal non-diabetic 105 women (mean age 63.4 +/- 8.1; range 52 to 64 years) with hip fracture were evaluated. Of these 105 patients, 46 had trochanteric fractures, 24 had subtrochanteric fractures and 35 had femoral neck fractures. Anthropometric measurements were performed. Serum adiponectin level was measured by means of ELISA. Total bone mineral density and bone mineral content of lumbar spine and proximal femur were measured by dual-energy X-ray absorptiometry (DEXA). Results: Lumbar bone mineral density and proximal femoral bone mineral density were not correlated with serum adiponectin levels. Serum adiponectin level was not found to have any significant effect on bone mass. Serum adiponectin levels were not significantly different between the patients with osteoporotic fractures and those with non-osteoporotic fractures. Conclusion: Our study showed that serum adiponectin level is not associated with bone mass and osteoporotic fracture risk. Investigation of local adiponectin levels in bony tissue is needed to clarify the possible relation between adiponectin and bone mass, and risk of fractures associated with osteoporosis.
Açıklama
Anahtar Kelimeler
Adiponectin, anthropometry, bone mineral density, osteoporosis, DEXA
Kaynak
Eklem Hastaliklari Ve Cerrahisi-Joint Diseases And Related Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
20
Sayı
2
Künye
Özkurt, B., Özkurt, Z. N., Altay, M., Aktekin, C. N., Çağlayan, O., Tabak, Y. (2009). The relationship between serum adiponectin level and anthropometry, bone mass, osteoporotic fracture risk in postmenopausal women. Eklem Hastalıkları ve Cerrahisi Dergisi (Eski Adı: Artroplasti Artroskopik Cerrahi Derg.), 20(2), 78 - 84.
