Therapeutic effect of some natural active compounds for breast cancer
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Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Humana Press Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The extracts obtained from plants have been used in the treatment of many diseases since the earliest times. Today, it is of great importance to investigate the effects of the active molecules in these plant extracts at the molecular level together with the analysis. The effect of certain active compounds found in some plants, widely used as medicinal plants, on breast cancer has been investigated using docking. As a result of the docking scores obtained, it can be understood that the active molecules used in this study can be quite effective in controlling breast cancer. Promyelocytic leukemia is an important checkpoint from the literature for breast cancer and the docking energy values of Thymoquinone, Piperine and Carvacrol, as the active molecules in the control of this pathway. This study is very important when evaluated in terms of directing experimental studies by determining the most suitable active substances by comparing the activities of molecules in a short time.
Açıklama
Anahtar Kelimeler
Breast cancer; Carvacrol; Docking; Thymol; Thymoquinone; Piperine
Kaynak
Medical Oncology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
39
Sayı
8
