Therapeutic effect of some natural active compounds for breast cancer

dc.authoridgokalp, faik/0000-0003-4363-3839
dc.contributor.authorGokalp, Faik
dc.date.accessioned2025-01-21T16:55:24Z
dc.date.available2025-01-21T16:55:24Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe extracts obtained from plants have been used in the treatment of many diseases since the earliest times. Today, it is of great importance to investigate the effects of the active molecules in these plant extracts at the molecular level together with the analysis. The effect of certain active compounds found in some plants, widely used as medicinal plants, on breast cancer has been investigated using docking. As a result of the docking scores obtained, it can be understood that the active molecules used in this study can be quite effective in controlling breast cancer. Promyelocytic leukemia is an important checkpoint from the literature for breast cancer and the docking energy values of Thymoquinone, Piperine and Carvacrol, as the active molecules in the control of this pathway. This study is very important when evaluated in terms of directing experimental studies by determining the most suitable active substances by comparing the activities of molecules in a short time.
dc.description.sponsorshipKirikkale University
dc.description.sponsorshipThe study of the author has been supported by Kirikkale University.
dc.identifier.doi10.1007/s12032-022-01704-0
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue8
dc.identifier.pmid35674845
dc.identifier.scopus2-s2.0-85131772534
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1007/s12032-022-01704-0
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25777
dc.identifier.volume39
dc.identifier.wosWOS:000808339400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc
dc.relation.ispartofMedical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectBreast cancer; Carvacrol; Docking; Thymol; Thymoquinone; Piperine
dc.titleTherapeutic effect of some natural active compounds for breast cancer
dc.typeArticle

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