Human hepatocyte growth factor levels in patients undergoing thoracic operations

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dc.contributor.authorDikmen, E.
dc.contributor.authorKara, M.
dc.contributor.authorKısa, Ü.
dc.contributor.authorAtinkaya, C.
dc.contributor.authorHan, S.
dc.contributor.authorSakinci, U.
dc.date.accessioned2020-06-25T17:41:11Z
dc.date.available2020-06-25T17:41:11Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810
dc.description.abstractHuman hepatocyte growth factor (hHGF) is the most potent mitogen identified for alveolar type II cells, and may have other important functions in the repair of the alveolar epithelium and compensatory lung growth. A study was conducted to evaluate the changes of serum hHGF levels in patients who underwent thoracic surgical procedures. The patients comprised 17 males and 14 females with a mean age of 47.1 +/- 13.5 yrs, who underwent either lung resection (LR group) or nonlung resection (norLR group) thoracic procedures. The changes of hHGF levels were analysed in the pre- and post-operative periods in both groups. The pre-operative hHGF levels did not differ between the LR and the nonLR groups, which were 333.2 +/- 72.9 pg center dot mL(-1) and 343.6 +/- 125.3 pg center dot mL(-1), respectively. The hHGF levels in the LR group significantly increased up to 433.6 +/- 128.1 pg center dot mL(-1) and 430.8 +/- 128.2 pg center dot mL(-1) in post-operative days 1 and 3, respectively. However, the same levels in the nonLR group appeared as 333.2 +/- 77.0 pg center dot mL(-1) and 311.9 +/- 73.0 pg center dot mL(-1), respectively. In conclusion, the increases of serum human hepatocyte growth factor levels following pulmonary resection may imply the important role of human hepatocyte growth factor in lung regeneration or compensatory lung growth in humans.en_US
dc.identifier.citationDikmen, E., Kara, M., Kisa, U., Atinkaya, C., Han, S., & Sakinci, U. (2006). Human hepatocyte growth factor levels in patients undergoing thoracic operations. The European respiratory journal, 27(1), 73–76. https://doi.org/10.1183/09031936.06.00148704en_US
dc.identifier.doi10.1183/09031936.06.00148704
dc.identifier.endpage76en_US
dc.identifier.issn0903-1936
dc.identifier.issue1en_US
dc.identifier.pmid16387938
dc.identifier.scopus2-s2.0-30744435877
dc.identifier.scopusqualityQ1
dc.identifier.startpage73en_US
dc.identifier.urihttps://doi.org/10.1183/09031936.06.00148704
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3651
dc.identifier.volume27en_US
dc.identifier.wosWOS:000234635100013
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherEuropean Respiratory Soc Journals Ltden_US
dc.relation.ispartofEuropean Respiratory Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecthepatocyte growth factoren_US
dc.subjectpulmonary resectionen_US
dc.subjectsurgeryen_US
dc.titleHuman hepatocyte growth factor levels in patients undergoing thoracic operationsen_US
dc.typeArticle

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