Evaluation of the Effect of Different Doses of Butaphosphan and Cyanocobalamin Combination in Dairy Cattle with Subclinical Ketosis

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dc.contributor.authorSahal, Mehmet
dc.contributor.authorDeniz, Abdulkerim
dc.contributor.authorVural, Rifat
dc.contributor.authorKuplulu, Sukru
dc.contributor.authorPolat, Ibrahim Mert
dc.contributor.authorColakoglu, Ekrem Cagatay
dc.contributor.authorOcak, Marion
dc.date.accessioned2020-06-25T18:23:03Z
dc.date.available2020-06-25T18:23:03Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.descriptionDeniz, Abdulkerim/0000-0002-5242-5671; colakoglu, ekrem cagatay/0000-0003-2789-035X; PEKCAN, MERT/0000-0003-3084-125X
dc.description.abstractThis study was conducted to assess the effects of different doses of butaphosphan-cyanocobalamin combination onbody condition score (BCS), beta-hydroxybutyrate (BHBA) and reproductive parameters in cows with subclinical ketosis (SCK). Holstein-Friesen cows (n=544) were checked for BHBA concentration. Cows with SCK (n=53, BHBA ranging from 1.00 to 3.00 mmol/L) were assigned randomly to receive saline (C0, n= 18), 5 mL/100 kg BW (C5, n=18) or 10 mL/100 kg BW (C10, n=17) butaphosphan-cyanocobalamin combination. BHBA concentration was measured on d 0, 10, and 18 relative to treatment application. BCS was evaluated weekly until d 60 postpartum. For reproductive parameters cows were monitored until d 150 postpartum. The median reduction in blood BHBA concentrations was 28, 57, and 75% for C0, C5, and C10, respectively. NEFA and total bilirubin concentrations were significantly decreased in C10 group. The relative median change in BCS as compared to baseline was 17, 12, and 6% for C0, C5, and C10, respectively. Between d 15 and 25 postpartum uterine involution was completed in 44, 83, and 88% of cows in groups C0, C5, and C10, respectively. Interval from calving to first insemination in group C10 was shorter than control group. Overall pregnancy rate was not different among groups. In conclusion butaphosphan-cyanocobalamin combination decreased severity of hyperketonemia, stimulated uterine involution, shortened time to first insemination and increased pregnancy rate.en_US
dc.description.sponsorshipBayer Animal Health, GermanyBayer AG [D12B12000058]; Ankara University Scientific Research Projects Coordination UnitAnkara University [2010ABH06739001]en_US
dc.description.sponsorshipThis study was supported by Bayer Animal Health, Germany (Project number: D12B12000058) and Ankara University Scientific Research Projects Coordination Unit (Project number: 2010ABH06739001)en_US
dc.identifier.citationŞahal M., Deniz A., Vural R., Küplülü Ş., Polat İ. M., Çolakoğlu E. Ç., Öcal N., Macun H. C., Pekcan M., Ocak M. (2017). Evaluation of the Effect of Different Doses of Butaphosphan and Cyanocobalamin Combination in Dairy Cattle with Subclinical Ketosis. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 23(3), 349 - 356.en_US
dc.identifier.doi10.9775/kvfd.2016.16651
dc.identifier.endpage356en_US
dc.identifier.issn1300-6045
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85014613040
dc.identifier.scopusqualityQ3
dc.identifier.startpage349en_US
dc.identifier.trdizinid219484
dc.identifier.urihttps://doi.org/10.9775/kvfd.2016.16651
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6991
dc.identifier.volume23en_US
dc.identifier.wosWOS:000399881500001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBeta hydroxybutyrateen_US
dc.subjectButaphosphanen_US
dc.subjectCyanocobalaminen_US
dc.subjectSubclinical ketosisen_US
dc.subjectReproductive performanceen_US
dc.titleEvaluation of the Effect of Different Doses of Butaphosphan and Cyanocobalamin Combination in Dairy Cattle with Subclinical Ketosisen_US
dc.typeArticle

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