Cranial bone regeneration via BMP-2 encoding mesenchymal stem cells
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Cranial bone repair and regeneration via tissue engineering principles has attracted a great deal of interest from researchers during last decade. Here, within this study, 6mm critical-sized bone defect regeneration via genetically modified mesenchymal stem cells (MSC) were monitored up to 4 months. Cranial bone repair and new bone formations were evaluated by histological staining and real time PCR analysis in five different groups including autograft and bone morphogenetic protein-2 (BMP-2) transfected MSC groups. Results presented here indicate a proper cranial regeneration in autograft groups and a prospering regeneration for hBMP-2 encoding mesenchymal stem cells.
Açıklama
Odabas, Sedat/0000-0002-7844-7019; KORKUSUZ, PETEK/0000-0002-7553-3915
Anahtar Kelimeler
Bone morphogenetic protein-2, cranial bone regeneration, critical size defect, mesenchymal stem cell, transfection
Kaynak
Artificial Cells Nanomedicine And Biotechnology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
45
Sayı
3
Künye
Altugan Cahit Vural, Sedat Odabas, Petek Korkusuz, Atiye Seda Yar Sağlam,
Elif Bilgiç, Tarık Çavuşoğlu, Erhan Piskin & İbrahim Vargel (2017) Cranial bone regeneration via
BMP-2 encoding mesenchymal stem cells, Artificial Cells, Nanomedicine, and Biotechnology,
45:3, 544-550.
