Intracranial Lesions in Children and Adolescents with Morbid Obesity

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dc.contributor.authorErgur, Ayca Torel
dc.contributor.authorGunes, Sevinc Odabasi
dc.contributor.authorTan, Sinan
dc.contributor.authorTandircioglu, U. Ayse
dc.date.accessioned2020-06-25T18:23:08Z
dc.date.available2020-06-25T18:23:08Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Intracranial lesions may affect the hypothalamo-hypophyseal axis and lead to some neuroendocrinological dysfunctions (hyperphagia, sleep disorders and hormonal dysfunctions). There is a very limited number of studies about childhood obesity and intracranial lesions. Aims: To evaluate the incidence of intracranial lesions and its role in clinical symptoms and aetiology in cases with morbid obesity who have been admitted to the paediatric endocrinology department with this complaint. Study Design: Cross-sectional study. Methods: A total of 120 cases admitted to the paediatric endocrinology department with the complaint of morbid obesity between 2002 and 2015 were included in this study. A detailed history was taken and a physical examination was performed; biochemical, hormonal parameters were evaluated. Contrast dynamic magnetic resonance imaging was performed in order to visualize cranial pathologies. Results: An intracranial lesions was detected in 16.6% of the patients and 55% of these lesions were adenoma of the hypophysis. Prolactin levels were increased in six patients but front hypophyseal hormone levels were within normal range in the rest of the patients. Growth velocity of the patients was not affected. Conclusion: In our study, the incidence of intracranial lesions in children and adolescents with morbid obesity was much higher than in the normal population. According to this data, we are of the opinion that contrast dynamic magnetic resonance imaging is helpful in children with morbid obesity for the early detection of the mass before it causes any clinical or neurological symptoms and in the prevention of future complications.en_US
dc.identifier.citationErgür A. T., Güneş S. O., Tan S., Tandırcıoğlu Ü. A. (2017). Intracranial Lesions in Children and Adolescents with Morbid Obesity. Balkan Medical Journal, 34(2), 108 - 112.en_US
dc.identifier.doi10.4274/balkanmedj.2015.1541
dc.identifier.endpage112en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue2en_US
dc.identifier.pmid28418336
dc.identifier.scopus2-s2.0-85016414741
dc.identifier.scopusqualityQ1
dc.identifier.startpage108en_US
dc.identifier.trdizinid229731
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.2015.1541
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7017
dc.identifier.volume34en_US
dc.identifier.wosWOS:000400660600003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofBalkan Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIntracranial lesionsen_US
dc.subjectchildrenen_US
dc.subjectmorbid obesityen_US
dc.subjectmagnetic resonance imagingen_US
dc.titleIntracranial Lesions in Children and Adolescents with Morbid Obesityen_US
dc.typeArticle

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