Early Inflammation Related to Pediatric Obesity
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Dosyalar
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aves Yayincilik, Ibrahim Kara
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Obesity is a serious health problem, has reached pandemic proportions and represents a major risk for several comorbidities. Some of the serum markers are considered to be associated with low-grade chronic inflammation. Neutrophil to lymphocyte ratio (NLR) is a new and cost-effective marker for the detection of subclinical inflammation that correlates with C-reactive protein (CRP) levels. The objectives of this study were to examine the relation between children's BMI and the bio-markers of early inflammatory predictors.Material and Methods: The retrospective study included 176 children aged 5-18 years who applied to a primary care setting in Turkiye be-tween January 2019 and March 2019. Participants with BMIs between 85-95 percentiles were defined as overweight and those over 95 per-centiles as obese. For all groups, hemogram parameters, cell volumes, and ratios were evaluated and compared. In addition, NLR and PLR were compared.Results: We found that neutrophil count and NLR were significantly different between the normal weight and overweight/obese groups (p= 0.001, p< 0.001 respectively) while hemoglobin, WBC, MPV, MCV, RDW, and PLR were similar in hemogram evaluation.Conclusion: Obesity is associated with low-grade inflammation levels and is reaching alarming rates among both children and adults. Our study suggested that neutrophil counts and NLR were significantly higher in overweight/obese children. Obesity-related studies involving pediatric patients are crucial to developing appropriate methods for preventing the development of further complications in adulthood.
Açıklama
Anahtar Kelimeler
Obesity; childhood; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio
Kaynak
Journal of Pediatric Infection
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
17
Sayı
1
