Early Inflammation Related to Pediatric Obesity

Basit Öğe Kaydı
dc.authoridKarahan, İrfan/0000-0003-4669-1751
dc.authoridDerhem, Baki/0000-0002-6989-9873
dc.contributor.authorDerhem, Baki
dc.contributor.authorKarahan, İrfan
dc.date.accessioned2025-01-21T16:33:38Z
dc.date.available2025-01-21T16:33:38Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: Obesity is a serious health problem, has reached pandemic proportions and represents a major risk for several comorbidities. Some of the serum markers are considered to be associated with low-grade chronic inflammation. Neutrophil to lymphocyte ratio (NLR) is a new and cost-effective marker for the detection of subclinical inflammation that correlates with C-reactive protein (CRP) levels. The objectives of this study were to examine the relation between children's BMI and the bio-markers of early inflammatory predictors.Material and Methods: The retrospective study included 176 children aged 5-18 years who applied to a primary care setting in Turkiye be-tween January 2019 and March 2019. Participants with BMIs between 85-95 percentiles were defined as overweight and those over 95 per-centiles as obese. For all groups, hemogram parameters, cell volumes, and ratios were evaluated and compared. In addition, NLR and PLR were compared.Results: We found that neutrophil count and NLR were significantly different between the normal weight and overweight/obese groups (p= 0.001, p< 0.001 respectively) while hemoglobin, WBC, MPV, MCV, RDW, and PLR were similar in hemogram evaluation.Conclusion: Obesity is associated with low-grade inflammation levels and is reaching alarming rates among both children and adults. Our study suggested that neutrophil counts and NLR were significantly higher in overweight/obese children. Obesity-related studies involving pediatric patients are crucial to developing appropriate methods for preventing the development of further complications in adulthood.
dc.identifier.doi10.5578/ced.20239916
dc.identifier.endpage13
dc.identifier.issn1307-1068
dc.identifier.issn1308-5271
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85153316302
dc.identifier.scopusqualityQ4
dc.identifier.startpage9
dc.identifier.trdizinid1178161
dc.identifier.urihttps://doi.org/10.5578/ced.20239916
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1178161
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23821
dc.identifier.volume17
dc.identifier.wosWOS:000975510800002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAves Yayincilik, Ibrahim Kara
dc.relation.ispartofJournal of Pediatric Infection
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectObesity; childhood; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio
dc.titleEarly Inflammation Related to Pediatric Obesity
dc.title.alternativePediyatrik Obezite İlişkili Erken Enflamasyon
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin/Full Text
Boyut:
112.32 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu