Rathke Cleft Cyst in Seven Year-old Girl Presenting with Central Diabetes Insipidus and Review of Literature

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dc.contributor.authorEvliyaoglu, Olcay
dc.contributor.authorEvliyaoglu, Çetin
dc.contributor.authorAyva, Sebnem
dc.date.accessioned2020-06-25T17:51:15Z
dc.date.available2020-06-25T17:51:15Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.descriptionEVLIYAOGLU, CETIN AYHAN/0000-0002-1774-3084
dc.description.abstractRathke cleft cysts (RCC) are benign cysts derived from remnants of Rathke cleft, and are rarely symptomatic in children. Symptoms due to RCC are associated with mass effect and pituitary hormone deficiencies. Slow growth rate of the cyst makes its incidence increase with aging. Here we report on a seven year old girl who presented with central diabetes insipidus (CDI). Her sella MRI revealed a lesion in the sellar region which grew rapidly in follow-up. She underwent microneurosurgical operation and the lesion was totally excised. Pathologic examination revealed RCC with degenerative changes. In her follow-up, growth hormone deficiency developed in addition to arginine vasopressin deficiency. Rapid growth of the cyst is not the usual course of RCC's. Mechanisms regarding the cyst growth are unclear as they are in this case. This is the youngest child to date presenting with central diabetes insipidus due to RCC. Rapid growth of RCC can cause CDI in young children.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1515/jpem.2010.087
dc.identifier.endpage529en_US
dc.identifier.issn0334-018X
dc.identifier.issue5en_US
dc.identifier.pmid20662355
dc.identifier.scopus2-s2.0-77954506946
dc.identifier.scopusqualityQ2
dc.identifier.startpage525en_US
dc.identifier.urihttps://doi.org/10.1515/jpem.2010.087
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4754
dc.identifier.volume23en_US
dc.identifier.wosWOS:000279510100017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFreund Publishing House Ltden_US
dc.relation.ispartofJournal Of Pediatric Endocrinology & Metabolism
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRathke cleft cysten_US
dc.subjectcentral diabetes insipidusen_US
dc.titleRathke Cleft Cyst in Seven Year-old Girl Presenting with Central Diabetes Insipidus and Review of Literatureen_US
dc.typeArticle

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