Adiponectin and insulin resistance in obesity-related diseases

dc.contributor.authorEbinc, H.
dc.contributor.authorOzkurt, Z. N.
dc.contributor.authorEbin, F. A.
dc.contributor.authorYilmaz, M.
dc.contributor.authorCaglayan, O.
dc.date.accessioned2020-06-25T17:48:03Z
dc.date.available2020-06-25T17:48:03Z
dc.date.issued2008
dc.description.abstractThe relationship between insulin resistance and serum adiponectin levels in 400 subjects with different obesity-related diseases was studied. Lean subjects with body mass index (BMI) < 25 kg/m(2) were placed in one group and the other five groups of overweight/obese subjects with BMI >= 25 kg/m(2) were grouped according to disease profile. The homeostasis model assessment insulin resistance (HOMA-IR) index and adiponectin levels were similar in the lean, metabolically normal (MNO) and hypertensive groups, but were different when the dyslipidaemic group was compared with the lean and MNO groups. The type 2 diabetic (DMO) and hypertensive, type 2 diabetic (DMHTO) groups were significantly different from other groups with respect to HOMA-IR index and adiponectin levels. Adiponectin levels were lower in the DMHTO than the DMO group. In multiple regression analysis, adiponectin levels correlated with group categorization independently of age, sex, BMI and HOMA-IR. Hypoadiponectinaemia may play a role in the development of complications of obesity.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1177/147323000803600110
dc.identifier.endpage79en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue1en_US
dc.identifier.pmid18230270
dc.identifier.scopus2-s2.0-39149092063
dc.identifier.scopusqualityQ2
dc.identifier.startpage71en_US
dc.identifier.urihttps://doi.org10.1177/147323000803600110
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4271
dc.identifier.volume36en_US
dc.identifier.wosWOS:000253171700010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of International Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectobesityen_US
dc.subjectobesity-related diseasesen_US
dc.subjectinsulin resistanceen_US
dc.subjectadiponectinen_US
dc.titleAdiponectin and insulin resistance in obesity-related diseasesen_US
dc.typeArticle

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