Doxycycline-induced staining of permanent adult dentition

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dc.contributor.authorAyashoglu, E
dc.contributor.authorErkek, E
dc.contributor.authorOba, AA
dc.contributor.authorCebecloglu, E
dc.date.accessioned2020-06-25T17:40:16Z
dc.date.available2020-06-25T17:40:16Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionOzturk Durmaz, Emel/0000-0003-0661-9720
dc.description.abstractBackground. Doxycycline, is the most, effective antibiotic for managing, brucellosis. Although it is relatively free from side, effects, complications involving the skin, nails-and teeth may rarely be encountered. Methods: Four patients with brucellosis developed yellow-brown discolouration of teeth following a 30-45 day course of doxycycline therapy during summer at a dose of 200mg/day. Results: All four patients were diagnosed as having doxycycline-induced staining of the permanent dentition. In all cases,, the staining completely resolved and the teeth recovered their original colour following abrasive dental cleaning. Conclusions: These observations indicate that the incidence of staining of the permanent dentition, as a complication of doxycycline, may be much higher than the literature indicates, especially if treatment is administered during summer, months. Fortunately, this complication is reversible and does not require termination of. doxycycline therapy. Complete resolution following abrasive cleaning may suggest that an extrinsic mechanism within the dental milieu may be involved in its pathogenesis. Strict avoidance of sunlight exposure during high-dose, long-term doxycycline therapy might prevent the development of this complication.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/j.1834-7819.2005.tb00373.x
dc.identifier.endpage275en_US
dc.identifier.issn0045-0421
dc.identifier.issn1834-7819
dc.identifier.issue4en_US
dc.identifier.pmid17016895
dc.identifier.scopus2-s2.0-30444440759
dc.identifier.scopusqualityQ2
dc.identifier.startpage273en_US
dc.identifier.urihttps://doi.org/10.1111/j.1834-7819.2005.tb00373.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3369
dc.identifier.volume50en_US
dc.identifier.wosWOS:000234307100012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofAustralian Dental Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttetracyclineen_US
dc.subjectdoxycyclineen_US
dc.subjectteeth stainingen_US
dc.subjectteeth discolourationen_US
dc.subjectside effectsen_US
dc.titleDoxycycline-induced staining of permanent adult dentitionen_US
dc.typeArticle

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