The Effects of Cadmium, Copper and Lead on In Vitro Bovine Uterine Contractility
Yükleniyor...
Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kafkas Univ, Veteriner Fakultesi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aim of this study was to investigate in vitro effects of cadmium, copper and lead on isolated bovine uterus contractions at follicular and luteal stage. In this study myometrial strips obtained from healthy Holstein cows slaughtered in Kirikkale slaughterhouse were used. The strips were mounted to isolated organ bath under a basal tension of 2 g. The effects of 10(-5) M cadmium, 10(-4) M copper and 10(-4) M lead on the spontaneous, 2.5 mIU/ml oxytocin and 10(-6) M PGF(2) alpha induced contractions were examined. At follicular stage, all contractility parameters (maximum and mean amplitudes and frequency) of uterine induced by oxytocin and prostaglandin F-2 alpha (PGF(2) alpha), and at the luteal stage all contractility parameters of spontaneous, oxytocin and PGF(2) alpha induced contractions were decreased significantly by cadmium. At follicular stage the maximum and mean amplitude of spontaneous contractions, all contractility parameters induced by oxytocin, the frequency and maximum amplitude caused by PGF(2) alpha and, at the luteal stage the maximum amplitude of spontaneous contractions, the frequency and maximum amplitude of uterine contractions induced by oxytocin, and maximum-mean amplitude of contractions induced by PGF(2) alpha were decreased by copper. While lead decreased the frequency of uterine contractions induced by PGF(2) alpha and oxytocin at folicular and luteal stage, at luteal stage it increased the mean amplitude of spontaneous contractions. It was suggested that cadmium, copper and lead changed the contractility of bovine uterine; therefore this may be effect the fertility in cattles.
Açıklama
Anahtar Kelimeler
Bovine uterus, In vitro, Cadmium, Copper, Lead
Kaynak
Kafkas Universitesi Veteriner Fakultesi Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
19
Sayı
5
Künye
Yıldırım E., Macun H. C. (2013). Kadmiyum, bakır ve kurşunun in vitro inek uterus kasılmaları üzerine etkileri. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 19(5), 793 - 799.
