The Effects of Cadmium, Copper and Lead on In Vitro Bovine Uterine Contractility

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dc.contributor.authorYildirim, Ebru
dc.contributor.authorMacun, Hasan Ceyhun
dc.date.accessioned2020-06-25T18:07:03Z
dc.date.available2020-06-25T18:07:03Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of this study was to investigate in vitro effects of cadmium, copper and lead on isolated bovine uterus contractions at follicular and luteal stage. In this study myometrial strips obtained from healthy Holstein cows slaughtered in Kirikkale slaughterhouse were used. The strips were mounted to isolated organ bath under a basal tension of 2 g. The effects of 10(-5) M cadmium, 10(-4) M copper and 10(-4) M lead on the spontaneous, 2.5 mIU/ml oxytocin and 10(-6) M PGF(2) alpha induced contractions were examined. At follicular stage, all contractility parameters (maximum and mean amplitudes and frequency) of uterine induced by oxytocin and prostaglandin F-2 alpha (PGF(2) alpha), and at the luteal stage all contractility parameters of spontaneous, oxytocin and PGF(2) alpha induced contractions were decreased significantly by cadmium. At follicular stage the maximum and mean amplitude of spontaneous contractions, all contractility parameters induced by oxytocin, the frequency and maximum amplitude caused by PGF(2) alpha and, at the luteal stage the maximum amplitude of spontaneous contractions, the frequency and maximum amplitude of uterine contractions induced by oxytocin, and maximum-mean amplitude of contractions induced by PGF(2) alpha were decreased by copper. While lead decreased the frequency of uterine contractions induced by PGF(2) alpha and oxytocin at folicular and luteal stage, at luteal stage it increased the mean amplitude of spontaneous contractions. It was suggested that cadmium, copper and lead changed the contractility of bovine uterine; therefore this may be effect the fertility in cattles.en_US
dc.identifier.citationYıldırım E., Macun H. C. (2013). Kadmiyum, bakır ve kurşunun in vitro inek uterus kasılmaları üzerine etkileri. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 19(5), 793 - 799.en_US
dc.identifier.doi10.9775/kvfd.2013.8805
dc.identifier.endpage799en_US
dc.identifier.issn1300-6045
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84880948013
dc.identifier.scopusqualityQ3
dc.identifier.startpage793en_US
dc.identifier.trdizinidtrdizinikyoktur
dc.identifier.urihttps://doi.org/10.9775/kvfd.2013.8805
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5458
dc.identifier.volume19en_US
dc.identifier.wosWOS:000328082700010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isotr
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBovine uterusen_US
dc.subjectIn vitroen_US
dc.subjectCadmiumen_US
dc.subjectCopperen_US
dc.subjectLeaden_US
dc.titleThe Effects of Cadmium, Copper and Lead on In Vitro Bovine Uterine Contractilityen_US
dc.typeArticle

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