Giant condyloma acuminata of Buschke-Lowenstein: successful treatment with a combination of surgical excision, oral acitretin and topical imiquimod
Yükleniyor...
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-Blackwell Publishing, Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Human papillomavirus (HPV) is the most common sexually transmitted disorder in young, sexually active populations in the USA and Europe. Giant condyloma acuminatum (GCA) is a unique variant of condyloma acuminata, characterized by local aggressive behaviour despite benign histology. It carries a substantial risk of squamous cell carcinoma. Various treatments have been used, but response is often poor and recurrence rates high. We present a case of GCA successfully treated with a combination of surgical excision, oral acitretin and topical imiquimod. The diagnosis was based on histological examination, immunohistochemical analysis and in situ hybridization for HPV 6 and 11. We recommend a trial of oral retinoid and topical imiquimod in selected cases of GCA.
Açıklama
emeksiz, can/0000-0002-0933-4619
Anahtar Kelimeler
Kaynak
Clinical And Experimental Dermatology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
34
Sayı
3
Künye
closedAccess
