Giant condyloma acuminata of Buschke-Lowenstein: successful treatment with a combination of surgical excision, oral acitretin and topical imiquimod

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dc.contributor.authorErkek, Emel
dc.contributor.authorBaşar, Halil
dc.contributor.authorBozdoğan, Önder
dc.contributor.authorEmeksiz, M. Can
dc.date.accessioned2020-06-25T17:48:29Z
dc.date.available2020-06-25T17:48:29Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.descriptionemeksiz, can/0000-0002-0933-4619
dc.description.abstractHuman papillomavirus (HPV) is the most common sexually transmitted disorder in young, sexually active populations in the USA and Europe. Giant condyloma acuminatum (GCA) is a unique variant of condyloma acuminata, characterized by local aggressive behaviour despite benign histology. It carries a substantial risk of squamous cell carcinoma. Various treatments have been used, but response is often poor and recurrence rates high. We present a case of GCA successfully treated with a combination of surgical excision, oral acitretin and topical imiquimod. The diagnosis was based on histological examination, immunohistochemical analysis and in situ hybridization for HPV 6 and 11. We recommend a trial of oral retinoid and topical imiquimod in selected cases of GCA.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/j.1365-2230.2008.02938.x
dc.identifier.endpage368en_US
dc.identifier.issn0307-6938
dc.identifier.issue3en_US
dc.identifier.pmid19175780
dc.identifier.scopus2-s2.0-62449095212
dc.identifier.scopusqualityQ2
dc.identifier.startpage366en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2008.02938.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4468
dc.identifier.volume34en_US
dc.identifier.wosWOS:000264163000021
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofClinical And Experimental Dermatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleGiant condyloma acuminata of Buschke-Lowenstein: successful treatment with a combination of surgical excision, oral acitretin and topical imiquimoden_US
dc.typeArticle

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