Gold and gold-palladium coated polypropylene grafts in a S-epidermidis wound infection model

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dc.contributor.authorSaygun, Oral
dc.contributor.authorAğalar, Canan
dc.contributor.authorAydınuraz, Kuzey
dc.contributor.authorAğalar, Fatih
dc.contributor.authorDaphan, Çağatay
dc.contributor.authorSaygun, Meral
dc.contributor.authorDenkbaş, Emir Baki
dc.date.accessioned2020-06-25T17:41:03Z
dc.date.available2020-06-25T17:41:03Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground. The use of non-absorbable mesh grafts in both abdominal wall defects and inguinal hernias are impossible in the presence of contamination. This study was conducted for evaluation of the efficiencies of polypropylene mesh grafts coated with gold and palladium-gold. Materials and methods. Ten piece of 1 x 2 cm. of polypropylene mesh grafts were used in each group of naive, gold-coated, and palladium-gold-coated. The grafts were incubated in physiological saline buffered and 0.5 McFarland slime positive Staphylococcus epidermidis for 24 h. At intervals of 6,12,24,48, 72 h grafts were washed with saline and vortexed for 2 min in 2 ml of physiological saline. There were 100 mu l of samples of vortexed material incubated in blood agar and 24 h later, colony numbers were assessed. In the second part of study, the grafts were implanted below the musculoaponeurotic layer at inguinal. region of rats following the same procedure of incubation and washing. On the 8th day, the rats were examined for infection rate and their wound cultures were obtained. Results. The least amount of bacterial growth was detected in the samples obtained from gold-palladium coated grafts; whereas the highest rate of growth was found in samples of naive grafts. The superficial surgical site infection rate was 0% in gold-palladium coated, 30% in gold-coated and 100% in naive polypropylene group. The bacterial growth rate from wound cultures confirmed the superficial surgical site infection rates in all groups. Conclusion. Prosthetic graft infection with S. epidermidis can be prevented by coating the graft with gold-palladium or gold. (c) 2006 Elsevier Inc. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.jss.2005.06.020
dc.identifier.endpage79en_US
dc.identifier.issn0022-4804
dc.identifier.issn1095-8673
dc.identifier.issue1en_US
dc.identifier.pmid16139304
dc.identifier.scopus2-s2.0-32444441694
dc.identifier.scopusqualityQ1
dc.identifier.startpage73en_US
dc.identifier.urihttps://doi.org/10.1016/j.jss.2005.06.020
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3618
dc.identifier.volume131en_US
dc.identifier.wosWOS:000235771200010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofJournal Of Surgical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectgolden_US
dc.subjectpalladiumen_US
dc.subjectS. epidermidisen_US
dc.subjectpolypropyleneen_US
dc.subjectforeign body infectionen_US
dc.titleGold and gold-palladium coated polypropylene grafts in a S-epidermidis wound infection modelen_US
dc.typeArticle

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