The value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitis

Basit Öğe Kaydı
dc.contributor.authorPehlivanli, Faruk
dc.contributor.authorAgalar, Fatih
dc.contributor.authorAgalar, Canan
dc.contributor.authorSaygun, Oral
dc.contributor.authorDaphan, Cagatay
dc.contributor.authorAydinuraz, Kuzey
dc.contributor.authorSahiner, Tayfun
dc.date.accessioned2020-06-25T17:51:40Z
dc.date.available2020-06-25T17:51:40Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi
dc.descriptionSahiner, Ibrahim Tayfun/0000-0002-3921-7675
dc.description.abstractBACKGROUND We aimed to investigate the impact of C-reactive protein (CRP), interleukin (IL)-6, leptin, cortisol, and caspase-3 on the decision of terminating planned abdominal repair in secondary peritonitis. METHODS Fifteen patients with peritonitis were enrolled into the study. Serum CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 activities were measured. RESULTS APACHE II scores at 48 hours (h) and age were significantly higher in non-survivors. A significant decrease was observed in caspase-3 activities of patients in whom <= 4 laparotomies were performed when compared with those who underwent >4 laparotomies. For patients who underwent <= 4 laparotomies, there was a significant difference in caspase-3 levels between 0 and 72 h. There was no significant difference in caspase-3 levels in non-survivors; caspase-3 levels were significantly lower in the survivors at 48 and 72 h. Changes in CRP, IL-6, leptin, and cortisol levels were not statistically significant. CONCLUSION CRP, IL-6, leptin, cortisol, and caspase-3 are not valuable in discriminating the number of planned operations, even though there is a significant decrease in caspase-3 "within" survivors. The discriminative value of caspase-3 for closure should be evaluated in studies in which caspase-3 is monitored for a longer duration in a large number of patients.en_US
dc.identifier.citationPehlivanlı, F., Ağalar, F., Ağalar, C., Saygun, O., Daphan, Ç. E., Aydınuraz, K., Büyükkoçak, Ü., Çağlayan, O., Dom, S., Şahiner, İ. T. (2011). The value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitis. Ulusal Travma ve Acil Cerrahi Dergisi, 17(5), 390 - 395.en_US
dc.identifier.doi10.5505/tjtes.2011.03443
dc.identifier.endpage395en_US
dc.identifier.issn1306-696X
dc.identifier.issue5en_US
dc.identifier.pmid22090322
dc.identifier.scopus2-s2.0-80054031700
dc.identifier.scopusqualityQ3
dc.identifier.startpage390en_US
dc.identifier.trdizinid126990
dc.identifier.urihttps://doi.org/10.5505/tjtes.2011.03443
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4951
dc.identifier.volume17en_US
dc.identifier.wosWOS:000295901400003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCaspase-3en_US
dc.subjectperitonitisen_US
dc.subjectplanned relaparotomyen_US
dc.subjectinterleukin-6en_US
dc.subjectcortisolen_US
dc.titleThe value of CRP, IL-6, leptin, cortisol, and peritoneal caspase-3 monitoring in the operative strategy of secondary peritonitisen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
fa3437c1-6df8-47b5-bebd-6eaf5d641792.pdf
Boyut:
1.66 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/Full text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Daha fazla yükle