Similar effects of general and spinal anaesthesia on perioperative stress response in patients undergoing haemorrhoidectomy

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dc.contributor.authorBüyükkoçak, Ünase
dc.contributor.authorCağlayan, Osman
dc.contributor.authorDaphan, Cağatay
dc.contributor.authorAydinuraz, Kuzey
dc.contributor.authorSaygun, Oral
dc.contributor.authorKaya, Tahsin
dc.contributor.authorAgalar, Fatih
dc.date.accessioned2020-06-25T17:41:14Z
dc.date.available2020-06-25T17:41:14Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSurgery induces release of neuroendocrine hormones (cortisol), cytokines (interleukin-6: IL-6, tumour necrosis factor-alpha: TNF-alpha), acute phase proteins (C-reactive protein: CRP, leptin). We studied the effects of general and spinal anaesthesia on stress response to haemorrhoidectomy. Patients were assigned to general and spinal anaesthesia groups (n = 7). Blood samples were drawn before induction and 24 hours after surgery. Perioperative levels of IL-6, TNF-alpha, CRP, cortisol, and leptin were comparable among the groups. Twenty four hours after surgery, TNF-alpha and cortisol did not change; IL-6 and CRP increased significantly in all patients. Significant increase in leptin levels was found in patients undergoing spinal anaesthesia. Except for the increase in leptin levels, there was no significant difference related to the effects of general and spinal anaesthesia. Copyright (c) 2006 Unase Buyukkocak et al.en_US
dc.identifier.citationBuyukkocak, U., Caglayan, O., Daphan, C., Aydinuraz, K., Saygun, O., & Agalar, F. (2006). Similar effects of general and spinal anaesthesia on perioperative stress response in patients undergoing haemorrhoidectomy. Mediators of inflammation, 2006(1), 97257. https://doi.org/10.1155/MI/2006/97257en_US
dc.identifier.doi10.1155/MI/2006/97257
dc.identifier.issn0962-9351
dc.identifier.issn1466-1861
dc.identifier.pmid16864910
dc.identifier.scopus2-s2.0-33645227784
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1155/MI/2006/97257
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3662
dc.identifier.volume2006en_US
dc.identifier.wosWOS:000240227900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Ltden_US
dc.relation.ispartofMediators Of Inflammation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleSimilar effects of general and spinal anaesthesia on perioperative stress response in patients undergoing haemorrhoidectomyen_US
dc.typeArticle

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